山西大学学报(自然科学版)2017,Vol.40Issue(2):331-335,5.DOI:10.13451/j.cnki.shanxi.univ(nat.sci.).2017.02.011
无水三氯化铝催化的吲哚自身偶联反应研究
Study on Homocoupling Reaction of Indoles using Anhydrous Aluminum Chloride as a Catalyst
摘要
Abstract
Instead of using proton acid or anhydride as the catalyst,a novel AlCl3-catalyzed homocoupling reaction of indoles was reported herein.This methodology features using low-cost catalyst,simple operation,high yields (86%-90%),and short reaction time (<40 min),which has applications in organic synthesis due to the atomic economic concerns (the atom utilization is 100%).The structure of products were characterized by 1H NMR spectra and 13C NMR spectra.In addition,a plausible mechanism of this reaction was proposed.关键词
合成方法/吲哚/无水三氯化铝/自身偶联Key words
synthetic method/indole/anhydrous aluminum chloride/homocoupling分类
化学化工引用本文复制引用
于静文,宋璐娜..无水三氯化铝催化的吲哚自身偶联反应研究[J].山西大学学报(自然科学版),2017,40(2):331-335,5.基金项目
山西医科大学校级科研基金项目(02201540) (02201540)