生殖医学杂志2017，Vol.26Issue(6)：557-561,5.DOI:10.3969/j.issn.1004-3845.2017.06.010
不同手术方式处理卵巢子宫内膜异位囊肿对体外受精-胚胎移植妊娠结局的影响
Effect of different surgical methods for treatment of ovary endometriosis cysts on pregnancy outcome of assisted reproductive technology
摘要
Abstract
Objective: To investigate the effect of different modus operandi (ovarian endometriosis cystectomy vs. ultrasound-guided transvaginal puncture of ovarian cyst) on the clinical outcome of IVF-ET. Methods: A retrospective analysis was performed on clinical data of 98 infertile patients less than 40 years old with ovary endometriosis cyst following assisted reproductive technology (ART) treatment. According to different operating ways,these patients were divided into ovarian endometriosis cystectomy group (cystectomy group,n=52) and ultrasound-guided transvaginal puncture of ovarian cyst group (puncture group,n=46). Another 55 infertile patients caused by tubal factor were recruited as the references (reference group). Then the ovulation induction and pregnancy outcome were analyzed between the two operation groups,and compared with the general IVF patients. Results: The number of antral follicles in the puncture group was significantly lower than that in the reference group [(10.41±4.69) vs. (13.68±7.78)](P<0.05). The E2 levels on HCG day in the cystectomy group [(15 746.24±7 821.86) pmol/L] and the puncture group [(16 704.57±7 860.99) pmol/L] were significantly lower than those in reference group [(21 082.45±10 316.09) pmol/L] (P<0.05). The number of oocytes retrieved from the cystectomy group [(11.37±5.98)] and the puncture group [(10.84±6.01)] was significantly less than the reference group [(14.05±7.27)](P<0.05). There were no significant differences in 2PN rate,the fertilization rate,the quality embryo rate and number of transplanted embryos among the three groups (P>0.05). The clinical pregnancy rate in the puncture group (39.13%) was lower than that of cystectomy group (53.85%),but it was not significantly different (P>0.05). Conclusions: The clinical outcomes of IVF-ET in the patients after operation of ovarian endometriosis cyst are similar with the general IVF patients. Ovarian endometriosis cystectomy and ultrasound-guided transvaginal puncture of ovarian cyst have their own advantages,and the appropriate treatment method should be chosen based on the actual situation of patients in clinical work.关键词
卵巢子宫内膜异位囊肿/囊肿剔除术/囊肿穿刺术/体外受精-胚胎移植Key words
Ovary endometriosis cyst/Ovarian cystectomy/Ovarian cyst puncture/IVF-ET引用本文复制引用
李艳梅,王乃辉,岳丰,马晓玲,张莉莉,张学红..不同手术方式处理卵巢子宫内膜异位囊肿对体外受精-胚胎移植妊娠结局的影响[J].生殖医学杂志,2017,26(6):557-561,5.基金项目
甘肃省自然科学基金(1606RJZA132) （1606RJZA132）
中央高校基本科研业务费(lzujbky-2013-155) （lzujbky-2013-155）
