西北国防医学杂志2017，Vol.38Issue(5)：297-300,4.DOI:10.16021/j.cnki.1007-8622.2017.05.006
2型糖尿病患者血清超氧化物歧化酶水平与血脂代谢关系的研究
Relationship between serum superoxide dismutase and lipid metabolism in patients with type 2 diabetes mellitus
叶夏云 1赵金英 1韩风霞1
作者信息
- 1. 解放军兰州总医院内分泌科,甘肃 兰州 730050
- 折叠
摘要
Abstract
Objective:To investigate the impact of serum superoxide dismutase on the lipid metabolism in type 2 diabetes mellitus(T2DM) patients stratified by blood glucose control.Methods:A total of 310 T2DM patients were enrolled and divided into three groups according to hemoglobinA1c (HbA1c) level:HbA1c＜7.0％ (n=72),HbA1c 7.0％-9.0％ (n=92),HbA1c≥9.0％ (n =146).120 healthy subjects were set as control group (NC).Serum SOD,HbA1c,FPG,LDL-C,TG,TC and non-high density lipoprotein (non-HDL-C) were measured.Results:H bA1c≥ 9.0 ％ group had higher levels of non-HDL-C and lower levels of superoxide dismutase(SOD) than HbA1c 7.0％-9.0％ group,HbA1c＜7.0％group and NC group.Non-HDL-C was positively correlated with BMI、FPG and HbA1c,and negatively correlated with SOD in T2DM patients.Multiple linear regression analysis showed that BMI、HbA1c and SOD were influence factors of non-HDL-C.Conclusion:The disorder of lipid metabolism showed a deteriorating trend with the increase of blood glucose.SOD was an influence factor of lipid metabolism with T2DM patients.关键词
糖尿病/超氧化物歧化酶/非高密度脂蛋白胆固醇Key words
diabetes mellitus/superoxide dismutase/non-high density lipoprotein分类
医药卫生引用本文复制引用
叶夏云,赵金英,韩风霞..2型糖尿病患者血清超氧化物歧化酶水平与血脂代谢关系的研究[J].西北国防医学杂志,2017,38(5):297-300,4.
