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医学营养治疗对肥胖型多囊卵巢综合征不孕症影响临床研究

窦攀 鞠慧岩 尚 李雪迎 薛晴 徐阳 郭晓蕙

中国实用内科杂志2017,Vol.37Issue(5):440-443,4.
中国实用内科杂志2017,Vol.37Issue(5):440-443,4.DOI:10.19538/j.nk2017050121

医学营养治疗对肥胖型多囊卵巢综合征不孕症影响临床研究

Effect of medical nutrition therapy on obese and infertile patients with polycystic ovary syndrome

窦攀 1鞠慧岩 2尚 2李雪迎 3薛晴 2徐阳 2郭晓蕙1

作者信息

  • 1. 北京大学第一医院临床营养科,北京100034
  • 2. 北京大学第一医院生殖与遗传医学中心,北京100034
  • 3. 北京大学第一医院医学统计室,北京100034
  • 折叠

摘要

Abstract

Objective To research the effect of medical nutrition therapy (MNT) on obese and infertile patients with polycystic ovary syndrome in body composition,endocrinology and metabolism and reproductive function,and to provide clinical basis and management experience of MNT for obese and infertile patients with PCOS.Methods Totally 110 cases of obese and infertile patients with PCOS were treated with MNT by a group practice pattern,which lasted for 12 weeks.Indicators of human body composition,endocrinology and metabolism and reproductive function before and after MNT were compared by pared-samples T test.Results After 12 weeks,index of obesity,such as body weight,waist circumference,BMI and body fat percentage,were significantly decreased (P<0.001).Endocrine and metabolism indexes,such as FPG,FIN,HOMA-IR,TG,TC and LDL-C and other indexes,were significantly decreased (P< 0.001).Reproductive function indexes,such as T,LH,LH/FSH,were also significantly decreased (P< 0.001).About 79.5% of the patients had improvement in menstrual cycle.Conclusion Twelve weeks of MNT can effectively reduce body weight and body fat percentage of obese and infertile patients with PCOS,and significantly improve endocrine and metabolism and reproductive function.MNT is an effective method for obese and infertile patients with PCOS.

关键词

肥胖/多囊卵巢综合征/医学营养治疗/限能量平衡膳食/人体成分

Key words

obesity/polycystic ovary syndrome/medical nutrition therapy/calorie restrict diet/body composition

分类

医药卫生

引用本文复制引用

窦攀,鞠慧岩,尚,李雪迎,薛晴,徐阳,郭晓蕙..医学营养治疗对肥胖型多囊卵巢综合征不孕症影响临床研究[J].中国实用内科杂志,2017,37(5):440-443,4.

中国实用内科杂志

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1005-2194

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