中国实用内科杂志2017，Vol.37Issue(5)：444-447,4.DOI:10.19538/j.nk2017050122
限能量平衡膳食对超重或肥胖多囊卵巢综合征患者体成分和代谢影响研究
Impact of calorie-restricted diet on body composition and metabolic parameters in overweight and obese PCOS patients
摘要
Abstract
Objective The study was to retrospective analysis of calorie-restricted diet (CRD) intervention on body composition and metabolic parameters in overweight and obese patients with polycystic ovary syndrome (PCOS).Methods The data of 59 overweight and obese adult females with PCOS according to the Rotterdam criteria were retrospectively analyzed,who received CRD therapy.At baseline and at 12 weeks,measure their body composition (InBody720),blood lipid,7Sg oral glucose tolerance test (OGTT) and synchronous insulin release test.Homeostasis model assessment of insulin resistance index (HOMA-IR) was calculated.Comparative analysis was done using paired T test and McNemar Chi square test.Results After 12 weeks of intervention,patients' body weight decreased (7.21±3.76)kg (9.05％).Body fat(BF),body fat percentage (BFP) and visceral fat area (VFA) decreased by 16.15％,8％ and 12.59％,respectively.Waist circumference (WC) decreased (7.00±4.12)cm (6.96％),and waist to hip ratio (WHR) decreased by 3.16％,P＜0.001.Total cholesterol (TC),low density lipoprotein cholesterol-C (LDL-C),triglyceride (TG),and insulin 0min and 120min all decreased significantly,and P values were ＜0.05.Insulin resistance (IR,defined as HOMA-IR ≥2.69) was detected in 89.83％ before the intervention,and 54.55％ after the intervention.The detection rate of MS was 67.80％ before the intervention,and 42.37％ after the intervention.Conclusions CRD intervention can reduce body weight,BF and VFA,and improve lipid metabolism disorder,IR and MS in overweight and obese patients with PCOS.关键词
限能量平衡膳食/超重或肥胖多囊卵巢综合征/体成分/代谢指标Key words
calorie-restricted diet/overweight and obese PCOS/body composition/metabolic parameters分类
医药卫生引用本文复制引用
王静,陈伟,孙海翔,朱大龙,沈山梅,毕艳,刘岩岩,周卫红..限能量平衡膳食对超重或肥胖多囊卵巢综合征患者体成分和代谢影响研究[J].中国实用内科杂志,2017,37(5):444-447,4.基金项目
南京市卫生局科技发展项目(YKK13075) （YKK13075）
