中国医学前沿杂志（电子版）2017，Vol.9Issue(4)：44-47,4.DOI:10.12037/YXQY.2017.04-11
动脉瘤介入栓塞术与颅内动脉瘤夹闭术治疗高分级动脉瘤性蛛网膜下腔出血的效果比较
The clinical efficacy of interventional embolization of aneurysm and clipping of intracranial aneurysm in the tratment of high grade aneurysmal subarachnoid hemorrhage
摘要
Abstract
Objective To compare and analyze the clinical efficacy and safety of interventional emboliz-ation of aneurysm clipping of intracranial aneurysms in the treatment of high grade aneurysmal subarachnoid hemorrhage (aSAH).Method 100 cases with World Federation of Neurosurgical Societies (WFNS) grade atⅣ~Ⅴ grade (high grade) enrolled in our hospital from October 2010 to October 2016 were randomly selected as the research objects. Patients were divided into embolization group and clipping group according to the operation methods, 50 cases in each group. Embolization group patients received endovascular embolization and stent embolization, and clipping group patients received clipping of aneurysm. The clinical outcomes of patients were evaluated with Glasgow outcome scale (GOS) 3 months after operation. The occurrence of hydrocephalus, rebleeding and cerebral vasospasm were recorded. Serum levels of immunoglobulin (Ig) G, IgA and IgM were detected by immunoassay in the two groups before and 3 days after operation.Result The favorable prognosis rate of the embolization group was significantly higher than that of clipping group (P<0.05), and the complication rate was significantly lower than that of clipping group (P<0.05). 3 days after operation, the levels of IgG, IgA and IgM in the two groups were significantly lower than those before operation (P<0.05), and the levels of IgG, IgA and IgM in clipping group weresignificantly lower than those in embolization group (P<0.05).Conclusion Compared with clipping of intracranial aneurysm, interventional embolization of intracranial aneurysm is more effective for the treatment of aSAH, with less complication, and has less influence on the immune function.关键词
介入栓塞术/颅内动脉瘤夹闭术/蛛网膜下腔出血/颅内动脉瘤Key words
Interventional embolization/Clipping of intracranial aneurysm/Subarachnoid hemorrhage/Intracranial aneurysm引用本文复制引用
李伦,黄昌仁..动脉瘤介入栓塞术与颅内动脉瘤夹闭术治疗高分级动脉瘤性蛛网膜下腔出血的效果比较[J].中国医学前沿杂志（电子版）,2017,9(4):44-47,4.基金项目
四川省科技创新苗子工程资助项目(2016065) （2016065）
