赵爽 1彭如臣 1沈秀芝 1张双 1钟佳利 1宋海龙1
作者信息
- 1. 首都医科大学附属北京潞河医院放射科,北京 101149
- 折叠
摘要
Abstract
Objective: To investigate the MR diffusion tensor imaging (DTI) as an application of quantitative analysis methods in lumbar intervertebral disc degeneration and the effects of different diffusion gradient directions (DGD) of DTI. Materials and Methods: Selected 50 patients with pain of waist or legs, including 32 male and 18 female, from 24 to 62 years old with mean age 46.9±16.2 years old, all the patients underwent sagittal scans for regular lumbar MRI and DTI, and with 6, 12, 20 DGD of DTI. According to the DGD, lumbar intervertebral discs can be divided into DD6, DD12, DD20 groups and divided lumbar intervertebral discs into Ⅱ, Ⅲ, Ⅳ, and Ⅴgroups by Pfirrmann grading system. ADC and FA and λ1 valuse were measured and analyzed among the different DGD groups and Pm groups. Results: There were no statistical difference of ADC values among the different DGD groups (P>0.05), while statistical difference of FA and λ1 values were found (P<0.05); DGD for 6, FA values were statistical differences among the different Pm groups (P<0.05), except Ⅳ andⅤ(P>0.05); DGD for 12 and 20, there were no statistical difference of FA values in all PM groups (P>0.05), except Ⅱ. DGD for 6, 12, 20, ADC values were statistical difference in all Pm groups, except Ⅱ and Ⅲ. In DGD for 6, 12, 20, λ1 values had no statistical difference in all Pm groups (P>0.05). Conclusion: DTI can be applied to the quantitative analysis of lumbar intervertebral disc, DGD for 6 can get high quality images and data in a relatively short time, and FA value can be used for quantitativeanalysis of different Pm grading lumbar intervertebral disc.关键词
磁共振成像/扩散张量成像/椎间盘退化/表观扩散系数Key words
Magnetic resonance imaging/Diffusion tensor imaging/Intervertebral disc degeneration/Apparent diffusion coefficient分类
医药卫生
