南方医科大学学报2017，Vol.37Issue(6)：792-796,5.DOI:10.3969/j.issn.1673-4254.2017.06.13
F10基因在宫颈癌组织中的表达
F10 expressions in cervical cancer tissues
摘要
Abstract
Objective To detect the expression of F10 at both mRNA and protein levels in cervical cancer tissues and explore its role in the occurrence and progression of cervical cancer. Methods F10 expressions at mRNA and protein levels were detected in 30 pairs of cervical cancer tissues and adjacent tissues using RT-PCR and immunohistochemistry. Results The mRNA and protein expressions of F10 were significantly higher in cervical cancer tissues than in the adjacent normal tissues (P<0.05). F10 expression was significantly higher in poorly differentiated cervical cancer than in well differentiated cancer tissues, and was also lower in patients with preoperative chemotherapy than in those without chemotherapy. Conclusion F10 expression level is inversely correlated with the differentiation of cervical cancer and possible plays a role in the tumorigenesis and progression of cervical cancer.关键词
F10基因/宫颈癌/表达分析Key words
F10/cervical cancer/expression analysis引用本文复制引用
张梦竹,庞战军..F10基因在宫颈癌组织中的表达[J].南方医科大学学报,2017,37(6):792-796,5.基金项目
国家自然科学基金(81170595) Supported by National Natural Science Foundation of China (81170595). （81170595）
