广东药学院学报2017，Vol.33Issue(3)：424-427,4.DOI:10.16809/j.cnki.1006-8783.2017020703
原发性肝癌病理类型与乙肝病毒感染模式和血清AFP含量的相关性研究
Correlation study on different pathological types of primary hepatic cancer and HBV infection patterns and the content of AFP
吴跃锐 1陈伟 2唐贝 3梁盛枝 2龚建安 2李荣2
作者信息
- 1. 南方医科大学南方医院肿瘤科,广东 广州 510515
- 2. 佛山市顺德区第二人民医院外三科,广东 佛山 528305
- 3. 中山大学附属第一医院肝胆外科,广东 广州 510080
- 折叠
摘要
Abstract
Objective To explore the correlation of different pathological types of primary hepatic cancer (PHC) and HBV infection patterns and the content of AFP.Methods The clinical data of patients with PHC received hepatectomy in three hospitals from January 2003 to December 2013 were retrospectively analyzed.All patients were divided into hepatocellular carcinoma group,cholangiocarcinoma group and other types of liver cancer group.The correlation between three pathological types of PHC and HBV infection patterns and the content of AFP was analyzed.Results There was no obvious correlation between age,gender and pathological types of PHC (X2=1.034,P=0.596;X2=1.360,P=0.5072).The levels of serum AFP were different in patients with different pathological types of primary liver cancer,and the serum AFP levels in patients with hepatocellular carcinoma were significantly higher than those of other pathological types (X2=99.65,P=0.000).There was obvious correlation between HBV infection patterns and pathological types of PHC.The positive results of HBsAg+HBcAb+HBeAb were highly associated with hepatocellular carcinoma,the positive results of HBsAg+HBeAg+HBcAb were associated with hepatocellular carcinoma and the positive results of HBsAb were also associated with cholangiocarcinoma group (P=0.000).Conclusion Pathological types of PHC were associated with HBV infection patterns and the content of AFP,which should be attracted more attentions by doctors and patients.关键词
原发性肝癌/乙型肝炎病毒/病理类型,AFPKey words
primary hepatic cancer/hepatitis B virus/pathological types,AFP分类
医药卫生引用本文复制引用
吴跃锐,陈伟,唐贝,梁盛枝,龚建安,李荣..原发性肝癌病理类型与乙肝病毒感染模式和血清AFP含量的相关性研究[J].广东药学院学报,2017,33(3):424-427,4.
