医学分子生物学杂志2017，Vol.14Issue(3)：181-186,6.DOI:10.3870/j.issn.1672-8009.2017.03.012
CNP/NPR-B/cGMP信号通路调控雌性生殖过程
CNP/NPR-B/cGMP Signalling Pathway Regulates the Female Reproductive Process
郭立丹 1黄东晖1
作者信息
- 1. 华中科技大学同济医学院计划生育研究所 武汉市,430030
- 折叠
摘要
Abstract
C-type natriuretic peptide (CNP) activates its cognate natriuretic peptide receptor B (NPR-B),stimulates the second messenger cyclic guanosine monophosphate (cGMP) production in cumulus cells and oocytes,and forms the CNP /NPR-B/cGMP signaling pathway,which can mediate a variety of physiological effects.In recent years,a large number of studies confirmed that CNP/NPR-B/cGMP signaling pathway is closely related to follicle development,oocyte meiosis and embryo development,suggesting that this signaling pathway may play a significant role in female reproductive process.关键词
C型利钠肽(CNP)/利钠肽受体B(NPR-B)/环磷酸鸟苷(cGMP)/雌性生殖Key words
C-type natriuretic peptide(CNP)/natriuretic peptide receptor B (NPR-B)/cyclic guanosine monophosphate (cGMP)/female reproduction分类
医药卫生引用本文复制引用
郭立丹,黄东晖..CNP/NPR-B/cGMP信号通路调控雌性生殖过程[J].医学分子生物学杂志,2017,14(3):181-186,6.
