光学精密工程2017，Vol.25Issue(5)：1159-1170,12.DOI:10.3788/OPE.20172505.1159
采用快速贝叶斯匹配追踪的单视图X射线发光断层成像
Single-view XLCT imaging based on fast Bayesian matching pursuit
摘要
Abstract
To relieve the ill-posedness of single-view x-ray luminescence computed tomography (XLCT), a fast Bayesian matching pursuit (FBMP) method combined with iterative-shrinking permissible region (ISPR) strategy was put forward.In this method, Bayesian model was combined with the greedy algorithm to quickly and efficiently restore sparse signal from few observed values.To further improve the reconstruction accuracy, FBMP was combined with ISPR strategy to simplify the mesh generation and system matrix construction by self-adaptive finite element, downsizing the factor iterative-shrinking permissible region, meanwhile relieving the ill-posedness of XLCT in reverse solution.In order to verify the effectiveness of the method, a simulation and a real physical phantom experiment were performed.The simulation results show that the proposed method, while speeding up the reconstruction process, significantly improve the localization accuracy of nano luminescent target and quantitative result of luminescence yield, which are 0.73 mm and 0.79 μg respectively.The physical phantom experiment further verifies the feasibility of this method in actual XLCT.关键词
光学分子影像/X射线发光断层成像/单视图重建/贝叶斯匹配追踪/可行区域迭代收缩Key words
optical molecular imaging/X-ray luminescence computed tomography/single-view reconstruction/Bayesian matching pursuit/iterative-shrinking permissible region分类
生物科学引用本文复制引用
侯榆青,曲璇,张海波,易黄建,贺小伟..采用快速贝叶斯匹配追踪的单视图X射线发光断层成像[J].光学精密工程,2017,25(5):1159-1170,12.基金项目
国家自然科学基金资助项目(No.61640418,No.61372046,No.61401264,No.11571012,No.61601363) （No.61640418,No.61372046,No.61401264,No.11571012,No.61601363）
陕西省科技计划项目(No.2013K12-20-12,No.2015KW-002) （No.2013K12-20-12,No.2015KW-002）
陕西省自然科学研究计划项目(No.2015JM6322) （No.2015JM6322）
陕西省教育厅自然科学研究计划项目(No.16JK1772) （No.16JK1772）
西北大学自然科学研究计划项目(No.338050018,No.334100032,No.338020012) （No.338050018,No.334100032,No.338020012）
