吉林中医药2017,Vol.37Issue(6):586-589,4.DOI:10.13463/j.cnki.jlzyy.2017.06.014
前列腺素在月经性偏头痛发病机制中的作用
Effect of prostaglandin in pathogenesis of menstrual migraine
摘要
Abstract
Menstrual migraine is a special type of migraine that is closely related to ovarian cycle. This accounts for about 65% of female migraine. Traditional Chinese Medicine thinks that menstrual migraine is related to the liver, spleen, kidney and the disorder ofChong andRen; Liver dysfunction, insufficiency of the spleen resulting in production of dampness, deficiency of kidney essence,qi and blood ofChong Ren running sluggish,Qingqiao dystrophy caused headache. It is relate with the change of the lever of estrogens, the calcitonin prime related peptide, gene in the modern medical research. At the same time, the prostaglandin (PG) is also one of the mainly reasons. Platelet aggregation, endothelial cells, 5-HT, etc. directly or indirectly affect how much prostaglandin production produces headaches. In this paper, the mechanism of the effect of prostaglandin on menstrual migraine and its correlation with primary dysmenorrhea were discussed.关键词
月经性偏头痛/前列腺素/内皮细胞/5-HT/痛经Key words
menstrual migraine/prostaglandin/endothelial cells/5-HT/dysmenorrhea分类
医药卫生引用本文复制引用
汪杏,杨紫艺,周梦媛,蔡力妍,徐韬,赵凌..前列腺素在月经性偏头痛发病机制中的作用[J].吉林中医药,2017,37(6):586-589,4.基金项目
国家自然科学基金(81473603). (81473603)