实用临床医药杂志2017，Vol.21Issue(9)：20-23,4.DOI:10.7619/jcmp.201709005
无抽搐电休克治疗对抑郁症患者认知功能的影响
Effects of modified electroconvulsive therapy on cognitive function of patients with depressive disorder
摘要
Abstract
Objective To explore the effect of modified electroconvulsive therapy (MECT) on cognitive function of patients with depression disorder.Methods Thirty-five depression patients were divided into MECT group and drug group.The MECT group was treated with MECT and SSRIs therapy,while the drug group was treated by SSRIs.HAMA,WCST,IGT and WAIS-RC were measuredat baseline at 2 weeks and 4 weeks afteRthe treatment,respectively.Results HAMD scores were significantly loweRthan the baseline afteRtreatment (P<0.05).There were no significant differences in IGT and WCST scores between the two groups at 2-week follow-up.However,there was significant difference at 4-week follow-up (P<0.05).There was also significant difference in WAIS-RC digit span scores among between MECT group and drug group at 2-week follow-up (P<0.05 oRP<0.01),but there was no significant difference at baseline and 4-week follow-up (P>0.05).Conclusion AfteRMECT treatment,the depression disordeRpatients′executive function and emotion decision function don′t change at the short term,but working memory decrease.MECT can improve executive function and emotion decision function of the depression patients at the long term,and it also has no impact on working memory.关键词
无抽搐电休克/抑郁症/认知功能Key words
modified electroconvulsive therapy/depression/cognitive function分类
医药卫生引用本文复制引用
王喆,唐小伟,周振和,袁国桢..无抽搐电休克治疗对抑郁症患者认知功能的影响[J].实用临床医药杂志,2017,21(9):20-23,4.基金项目
江苏省无锡市科技创新项目 (CSE31N1424) （CSE31N1424）
