实用临床医药杂志2017，Vol.21Issue(9)：28-30,34,4.DOI:10.7619/jcmp.201709007
肺康复训练联合吸入舒利迭与噻托溴铵对中重度COPD患者肺功能、运动耐力及生活质量的影响
Influence of pulmonary rehabilitation training combined with seretide and tiotropium bromide on pulmonary function, exercise endurance and quality of life in patients with moderate and severe COPD
摘要
Abstract
Objective To explore the effects of pulmonary rehabilitation training combined with seretide and tiotropium bromide on pulmonary function,exercise endurance and quality of life in patients with moderate and severe COPD.Methods A total of 80 patients with moderate and severe COPD were selected and randomly divided into rehabilitation group (n=40) and control group (n=40).The patients in both groups were treated with seretide and tiotropium bromide foR8 weeks.On this basis,the patients in the rehabilitation group were treated with pulmonary rehabilitation training.Pulmonary function was detected at the time points of on admission,the beginning of the training,and 2,4 and 8 weeks afteRtraining.The COPD assessment test (CAT) was also used to evaluate the patients′quality of life.Results Compared with the control group,the CAT score of the rehabilitation group was significantly loweRat 2,4 and 8 weeks (P<0.05).The percentage of forced expiratory volume in the first second (FEV1%Pre) was significantly higheRin the control group at the 4 weeks of treatment (P<0.05),but decreased at the end of treatment (P>0.05).In the rehabilitation group,maximal voluntary ventilation (MVV) and FEV1%FVC at the treatment of 2 weeks increased significantly (P<0.05),and compared with the control group,afteR8 weeks of treatment,pulmonary function indexes significantly improved in the rehabilitation group (P<0.05).In the rehabilitation group,the CAT score at the treatment of 2,4 and 8 weeks were significantly loweRthan the levels of the control group (P<0.05).Conclusion Pulmonary rehabilitation training combined with seretide and tiotropium bromide can alleviate severe airway obstruction and clinical symptoms in COPD patients,enhance exercise endurance,improve lung function and improve the quality of life.关键词
肺康复训练/舒利迭/噻托溴铵/慢性阻塞性肺疾病Key words
pulmonary rehabilitation training/seretide/tiotropium bromide/chronic obstructive pulmonary disease分类
医药卫生引用本文复制引用
江容飞,徐玲,李小华..肺康复训练联合吸入舒利迭与噻托溴铵对中重度COPD患者肺功能、运动耐力及生活质量的影响[J].实用临床医药杂志,2017,21(9):28-30,34,4.基金项目
四川省科技厅基金项目(2014JY0171) （2014JY0171）
