实用临床医药杂志2017，Vol.21Issue(9)：64-68,5.DOI:10.7619/jcmp.201709017
阿格列汀与吡格列酮联合治疗2型糖尿病的疗效及对胰岛β细胞功能改善的影响
Efficacy of alogliptin combined with pioglitazone in treatment of patients with type 2 diabetes and its influence on improvement of islet β cell function
虞欣1
作者信息
- 1. 北京市丰台医院 高干病房, 北京, 100070
- 折叠
摘要
Abstract
Objective To explore the efficacy of alogliptin combined with pioglitazone on treatment of patients with type 2 diabetes and its influence on improvement of islet β cell function.Methods A total of 79 T2DM patients were randomly divided into PBO group (n=26),ALO group (n=26) and ALO/PIO group (n=27).AfteR16 weeks of treatment,the clinical efficacy and changes of related indexes were compared.Results AfteR16 weeks of treatment,there were significant differences in FPG,2 h PG,HbAlc,HOMA-IRand HOMA-β among three groups (P<0.05).Conclusion Combined ALO/PIO therapy can improve glycemic control,reduce insulin resistance and improve islet β cell function.关键词
2型糖尿病/阿格列汀/吡格列酮/胰岛β细胞功能Key words
type 2 diabetes/alogliptin/pioglitazone/islet β cell function分类
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虞欣..阿格列汀与吡格列酮联合治疗2型糖尿病的疗效及对胰岛β细胞功能改善的影响[J].实用临床医药杂志,2017,21(9):64-68,5.
