实用临床医药杂志2017，Vol.21Issue(9)：113-115,122,4.DOI:10.7619/jcmp.201709029
右美托咪定联合舒芬太尼在骨科手术后镇痛中的效果
Effect of dexmedetomidine combined with sufentanil on postoperative analgesia foRpatients with orthopedic surgery
摘要
Abstract
Objective To evaluate the effect of dexmedetomidine combined with sufentanil on postoperative analgesia foRpatients with orthopedic surgery.Methods A total of 86 patients with orthopedic surgery were randomly divided into observation group and control group.The patients in the observation group were treated with dexmedetomidine combined with sufentanil foRpostoperative analgesia.The control group was treated with sufentanil foRpostoperative analgesia.The VAS and quantitative sensory testing (QST) were performed at different time points in both groups.The numbeRof postoperative patient-controlled analgesia,hemodynamics parameters,the adverse reaction and satisfaction degree were compared between the two groups.Results The VAS scores at T1 to T6 in control group were significantly higheRthan the observation group,the mechanical pain threshold was significantly loweRthan the observation group,and the HRand MAP were significantly higheRthan the observation group (P<0.05).The numbeRof patient-controlled analgesia,the dosage of sufentanil and the incidence rate of adverse reactions were significantly higheRin the control group than the observation group (P<0.05).The satisfactory degree of the observation group was significantly higheRthan the control group (P<0.05).Conclusion Dexmedetomidine can reduce the dosage of sufentanil and the incidence rate of side effects in treatment of patients with orthopedic surgery.关键词
骨科手术/舒芬太尼/右美托咪定/术后镇痛Key words
orthopedic surgery/sufentanil/dexmedetomidine/postoperative analgesia分类
医药卫生引用本文复制引用
孙慧芳,沈伯雄,罗海鸣..右美托咪定联合舒芬太尼在骨科手术后镇痛中的效果[J].实用临床医药杂志,2017,21(9):113-115,122,4.基金项目
上海市卫生系统优秀青年医学人才培养计划(PWRq2014-11) （PWRq2014-11）
