药学研究2017，Vol.36Issue(6)：353-355,359,4.DOI:10.13506/j.cnki.jpr.2017.06.012
基于纳米热疗剂的肿瘤热化疗研究进展
Research progress on tumor thermo-chemotherapy based on nano-hyperthermia agents
郭慧 1徐悦1
作者信息
- 1. 江苏大学药学院,江苏 镇江 212000
- 折叠
摘要
Abstract
As hyperthermia can enhance cytotoxicity of chemotherapeutic drug significantly,the thermo-chemotherapy,combining hyperthermia and chemotherapy,could achieve desired curative effect at lower drug dose.However,the efficiency of thermo-chemotherapy is determined completely by targeting hyperthermia in tumor tissue,which is limited by traditional whole-body heating.To overcome the shortage of traditional whole-body hyperthermia,some nano hyperthermia agents,converting infrared light or magnetic energy into thermal energy efficiently,have become promising candidates on targeting hyperthermia of tumor.Especially nano hyperthermia agents can be encapsulated with chemotherapeutic drugs simultaneously to form co-delivery,which could improve the synergetic efficiency of hyperthermia and chemotherapy.Therefore,thermo-chemotherapy based on nano-hyperthermia agents has been certificated as a promising cancer treatment.关键词
肿瘤化疗/肿瘤热疗/纳米热疗剂/热化疗Key words
Tumor chemotherapy/Hyperthermia/Nano-hyperthermia agents/Thermo-chemotherapy分类
医药卫生引用本文复制引用
郭慧,徐悦..基于纳米热疗剂的肿瘤热化疗研究进展[J].药学研究,2017,36(6):353-355,359,4.
