实用医学杂志2017，Vol.33Issue(8)：1262-1265,4.DOI:10.3969/j.issn.1006-5725.2017.08.018
基于ISHIM序列的IVIM-DWI成像在星形细胞肿瘤分级中的应用
Value of IVIM-DWI based on ISHIM sequence in astrocytic tumor grading
摘要
Abstract
Objective To investigate the value of intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) based on ISHIM sequence in the grading of astrocytic tumor.Methods We collected excised tumors confirmed by histological diagnosis from 42 patients including high-grade astrocytic tumors (10 WHO grade Ⅲ,18 WHO grade Ⅳ),and 14 low-grade astrocytic tumors (1 WHO grade Ⅰ and 13 WHO grade Ⅱ).All patients underwent conventional MR imaging,ISHIM IVIM-DWI,and contrast-enhanced MR imaging.Parameters of tumor parenchyma region,peripheral edema regions and the contralateral normal brain white matter sites were measured,and the statistical analysis was conducted.Results The D value in tumor parenchyma region was significantly lower,but the D* and f values were higher in high-grade astrocytic tumor when compared with lowgrade one and all had statistical significance;in tumor peripheral edema region,D value was lower in high-grade astrocytic tumor than that in low-grade one,and the difference had statistical significance but there was no significant difference in terms of the D* and f values.There was no significant difference of the D,D* and f values in contralateral normal brain white matter sites in both high-and low-grade astrocytic tumor.Conclusion The D,D* and f values measured by ISHIM IVIM-DWI are helpful to the judgment of tumor grade and it has greatapplication value in the differential diagnosis of high-and low-grade astrocytic tumor.关键词
IVIM-DWI/ISHIM/星形细胞肿瘤Key words
Intravoxel incoherent motion/Integrated specific slice dynamic Shim/Astrocytes tumor引用本文复制引用
张洁,姜兴岳,白岩,邹雪雪,聂泰明,杨明瑞,石清磊..基于ISHIM序列的IVIM-DWI成像在星形细胞肿瘤分级中的应用[J].实用医学杂志,2017,33(8):1262-1265,4.基金项目
山东省自然科学基金(编号:ZR2011HL038) （编号:ZR2011HL038）
