天津中医药大学学报2017，Vol.36Issue(3)：209-213,5.DOI:10.11656/j.issn.1673-9043.2017.03.13
UPLC-Q-TOF-MS/MS方法鉴定血必净注射液中20种化学成分
Simultaneous identification of 20 components in Xuebijing injection by UPLC-Q-TOF-MS/MS
摘要
Abstract
[Objective] To develop a UPLC-Q-TOF-MS/MS method for simultaneous identification of 20 components in Xuebijing injection. [Methods] The method of qualitative analysis was performed on ACQUITY UPLC? BEH C18 (2.1 mm×100 mm, 1.7μm) column with a gradient mobile phase system of acetonitrile and 0.1%formic acid. All of the analytes were identified in negative ionization. According to the high resolution MS spectra data, fragmentation ion information andretention time, 20 peaks were identified by comparison with reference standards data. [Results] Twenty components were identified in 45 min. [Conclusion] The established method for the identification of chemical constituents in Xuebijing injection is simple and accuracy.关键词
血必净注射液/UPLC-Q-TOF-MS/MS/定性分析Key words
Xuebijing injection/UPLC-Q-TOF-MS/MS/qualitative analysis分类
医药卫生引用本文复制引用
屠亚茹,欧阳慧子,孙梦杰,常艳旭,何俊..UPLC-Q-TOF-MS/MS方法鉴定血必净注射液中20种化学成分[J].天津中医药大学学报,2017,36(3):209-213,5.基金项目
国家自然科学基金项目资助(81303140). （81303140）
