现代医院2017，Vol.17Issue(5)：749-751,3.DOI:10.3969/j.issn.1671-332X.2017.05.040
尼卡地平对老年患者髋关节置换术后认知功能障碍的影响
Nicardipine′s Influence on Post Operation Cognitive Dysfunction in Senior Patient after Hip Joint Replacement Operation
刘海生 1张华 2缪叶 1黄敏 1罗艳1
作者信息
- 1. 解放军第一六九医院第198临床部 湖南郴州 423000
- 2. 解放军第一六九医院 湖南衡阳 421000
- 折叠
摘要
Abstract
Objective To discuss nicardipin′s influence on post operation cognitive dysfunction (POCD) in senior patient after hip joint replacement operation.Methods 180 senior patient, who received selective unilateral hip joint replacement operation between October 2015 and October 2016 under the condition of combined spinal-epidural anesthesia (CSEA) were randomly divided into Group A (with nicardipine) and Group B (without nicardipine).Nicardipine was only appropriately pumped into vein in time in Group A.MAP was observed and recorded 30 minutes after starting the operation and at the end of the operation.Mini-mental state examination (MMSE) was applied to score the patient one day before, one day, three days and five days after operation, and the number of POCD was recorded.Results Compared with Group B, Group A was obviously lower in MAP level (P<0.05) after 30 minutes.MMSE score of Group A was obviously higher (P<0.01) one day after operation.The number of POCD in Group A was 8 (8.89%) significantly lower than than that of Group B (19, 21.11%).Conclusion Nicardipine could maintain hemodynamic stability of senior patients receiving selective unilateral hip joint replacement operation under the CSEA and prevent POCD to a certain extent.关键词
尼卡地平/腰硬联合麻醉/老年患者/髋关节置换术/术后认知功能障碍Key words
Nicardipine/Combined Spinal-epidural Anesthesia/Senior Patient/Hip Joint Replacement Operation/Post Operation Cognitive Dysfunction分类
医药卫生引用本文复制引用
刘海生,张华,缪叶,黄敏,罗艳..尼卡地平对老年患者髋关节置换术后认知功能障碍的影响[J].现代医院,2017,17(5):749-751,3.
