中国医疗设备2017，Vol.32Issue(6)：74-78,86,6.DOI:10.3969/j.issn.1674-1633.2017.06.019
应用CTVision和千伏级CBCT研究鼻咽癌放疗摆位误差的比较分析
Comparative Analysis of Application of CTVision and Kilo-Voltage CBCT in the Nasopharyngeal Carcinoma Radiotherapy Beam Position Error
摘要
Abstract
Objective This paper aims to analyze the differences of setup error between CTVision and kilo-voltage cone-beam computer tomography (CBCT) comparatively, which used to calibrate the setup errors for nasopharyngeal carcinoma during radiotherapy. Methods A total number of 30 nasopharyngeal carcinoma patients, who underwent intensity-modulated radiation therapy (IMRT) with immobilization using a customized thermoplastic mask from January 2015 to August 2016, were randomly assigned to group A and group B, 15 cases. CTVision and kilo-voltage CBCT image-guided radiotherapy were performed in group A and group B respectively, once a week and 6 weeks each. If the setup error was>3 mm, setup errors were corrected by adjusting the treatment couch to match the treatment isocenter. Paired t-test was used to evaluate the differences. Results Regardless of the duration of the fractionated radiotherapy course, the setup errors in the LR, SI and AP directions were (0.44±2.26) , (0.45±2.29) , (-0.13±2.10) mm and (0.85±2.46), (0.50±2.64), (0.69±2.53) mm for group A and group B respectively, without significant differences between two groups (P>0.05). The Σ and σ of group A were 0.75~0.96 mm and 0.90~1.29 mm, respectively, and the Σ and σ of group B were 0.76~1.01 mm and 1.18~1.37 mm respectively. According to the formula of ICRU 62, Stroom and Van Herk, the MPTVs of group A were 1.32~1.51, 2.28~2.55 and 2.66~3.03 mm respectively, while 1.53~1.63, 2.45~2.85 and 2.83~3.35 mm were for group B. The MPTV in group B was slightly larger than those in group A, but the differences were not statistically significant (P>0.05). The MPRV based on the formula of McKenzie were 1.54~1.70 mm and 1.65~1.90 mm for group A and group B respectively. In addition, no significant differences in setup errors were observed during the fractionated radiotherapy course (P>0.05). Conclusion Application of CTVision and kilo-voltage CBCT can effectively correct the setup errors for nasopharyngeal carcinoma during radiotherapy. But there is no statistically significant difference between them. In clinical applications, this paper offer best choose for different patients and different body parts.关键词
CT加速器系统/锥形束CT/摆位误差/鼻咽癌/放疗Key words
CTVision/cone-beam computer temography/setup errors/nasopharyngeal carcinoma/radiotherapy分类
医药卫生引用本文复制引用
张全彬,彭莹莹,张书旭,梁有腾..应用CTVision和千伏级CBCT研究鼻咽癌放疗摆位误差的比较分析[J].中国医疗设备,2017,32(6):74-78,86,6.基金项目
广东省科技计划项目(2016A020215173) （2016A020215173）
广州市医药卫生科技一般引导项目(20151A010108) （20151A010108）
广州医科大学科学青年项目(2016A25). （2016A25）
