中国医疗设备2017，Vol.32Issue(6)：83-86,4.DOI:10.3969/j.issn.1674-1633.2017.06.021
基于Auto-Planning的宫颈癌调强放疗的剂量学研究
Dosimetric Study of Auto-Planning Based on Cervical Cancer Intensity-Modulated Radiotherapy
摘要
Abstract
Objective The purpose of this article was to study the dosimetry difference between the Auto-planning (AP) and conventional intensity-modulated radiotherapy (IMRT) in cervical cancer patients. Methods Ten grade I~Ⅲ cervical cancer patients were selected to perform the analysis. AP plan and IMRT plan were obtained by the Pinnacle3 V9.10 treatment planning system. The dose-volume histogram, homogeneity index, conformity index, and the doses that received by the organs at risk (OARs) were compared. Results Compared with the IMRT, the AP could generate treatment plan with lower target region Dmax, and the statistical difference of AP was significant (P=0.001). But no statistical difference was found in Dmin, Dmean, CI and HI of the target region. Superior results were found in bladder V50, rectum V50, Dmean, caput femoris V30 and Dmean with statistical difference (P<0.05). The V30, V40, V45 in bladder, V40 in rectum and caput femoris that texted by AP plan were lower than IMRT plan. Conclusions the AP plan could achieve similar target dose distribution to IMRT plan. Meanwhile, the AP plan could lower the highest dose in the target region. The hot spot and the illuminated of OARs were reduced at the same time.关键词
宫颈癌/剂量学差异/调强计划/危及器官/剂量成形结构Key words
cervical cancer/dosimetry difference/intensity-modulated radiotherapy/organs at risk/dose shaping structure分类
医药卫生引用本文复制引用
王琳婧,王锐濠,雷怀宇,李慧君,周露,张国前,张书旭..基于Auto-Planning的宫颈癌调强放疗的剂量学研究[J].中国医疗设备,2017,32(6):83-86,4.基金项目
广东省教育厅特色创新项目(2014KTSCX104) （2014KTSCX104）
广州市医药卫生科技项目(20161A011084). （20161A011084）
