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Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism

Ling Zhang Yue Hu Elizabeth Galella Frank P. Tomasella William P.Fish

药物分析学报(英文)2017,Vol.7Issue(3):156-162,7.
药物分析学报(英文)2017,Vol.7Issue(3):156-162,7.

Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism

Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism

Ling Zhang 1Yue Hu 2Elizabeth Galella 2Frank P. Tomasella 2William P.Fish2

作者信息

  • 1. Chemical and Synthetic Development, Bristol-Myers Squibb Co., New Brunswick, NJ 08903, USA
  • 2. Drug Product Science and Technology, Bristol-Myers Squibb Co.,New Brunswick, NJ 08903, USA
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摘要

关键词

Atropisomer separation/Chiral HPLC/Thermodynamic parameters/β-cyclodextrin stationary phase/Chiral separation mechanism

Key words

Atropisomer separation/Chiral HPLC/Thermodynamic parameters/β-cyclodextrin stationary phase/Chiral separation mechanism

引用本文复制引用

Ling Zhang,Yue Hu ,Elizabeth Galella ,Frank P. Tomasella ,William P.Fish..Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism[J].药物分析学报(英文),2017,7(3):156-162,7.

药物分析学报(英文)

OASCI

2095-1779

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