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Wnt信号通路在脊髓损伤修复中作用的实验研究进展

满夏楠 陈健尔

中国康复理论与实践2017,Vol.23Issue(6):645-648,4.
中国康复理论与实践2017,Vol.23Issue(6):645-648,4.DOI:10.3969/j.issn.1006-9771.2017.06.005

Wnt信号通路在脊髓损伤修复中作用的实验研究进展

Experimental Research Progress of Wnt Signaling Pathway in Spinal Cord Injury Repair (review)

满夏楠 1陈健尔1

作者信息

  • 1. 浙江中医药大学第三临床医学院,浙江杭州市310053
  • 折叠

摘要

Abstract

Wnt signaling pathway is one of the important signal transduction systems that involved in regulating nervous system devel-opment, which plays an important role in axonal regeneration, neural stem cell proliferation and differentiation into neurons and inhibition of differentiation into glial cells. After spinal cord injury, multiple Wnt protein expresses around the injury site, and some proteins of the Wnt family play an important role in spinal cord injury repair, in which the activation of Wnt/β-catenin signaling pathway is necessary for spinal cord regeneration after spinal cord injury.

关键词

Wnt信号通路/脊髓损伤/神经干细胞/Wnt/β-catenin通路/综述

Key words

Wnt signaling pathway/spinal cord injury/neural stem cells/Wnt/β-catenin pathway/review

分类

医药卫生

引用本文复制引用

满夏楠,陈健尔..Wnt信号通路在脊髓损伤修复中作用的实验研究进展[J].中国康复理论与实践,2017,23(6):645-648,4.

基金项目

1.浙江省公益性技术应用研究计划项目(No.2012C33066) (No.2012C33066)

2.浙江省中医药科技计划项目(No.2012ZA123). (No.2012ZA123)

中国康复理论与实践

OA北大核心CSCDCSTPCD

1006-9771

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