中国康复理论与实践2017,Vol.23Issue(6):645-648,4.DOI:10.3969/j.issn.1006-9771.2017.06.005
Wnt信号通路在脊髓损伤修复中作用的实验研究进展
Experimental Research Progress of Wnt Signaling Pathway in Spinal Cord Injury Repair (review)
摘要
Abstract
Wnt signaling pathway is one of the important signal transduction systems that involved in regulating nervous system devel-opment, which plays an important role in axonal regeneration, neural stem cell proliferation and differentiation into neurons and inhibition of differentiation into glial cells. After spinal cord injury, multiple Wnt protein expresses around the injury site, and some proteins of the Wnt family play an important role in spinal cord injury repair, in which the activation of Wnt/β-catenin signaling pathway is necessary for spinal cord regeneration after spinal cord injury.关键词
Wnt信号通路/脊髓损伤/神经干细胞/Wnt/β-catenin通路/综述Key words
Wnt signaling pathway/spinal cord injury/neural stem cells/Wnt/β-catenin pathway/review分类
医药卫生引用本文复制引用
满夏楠,陈健尔..Wnt信号通路在脊髓损伤修复中作用的实验研究进展[J].中国康复理论与实践,2017,23(6):645-648,4.基金项目
1.浙江省公益性技术应用研究计划项目(No.2012C33066) (No.2012C33066)
2.浙江省中医药科技计划项目(No.2012ZA123). (No.2012ZA123)