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长期应用质子泵抑制剂可能增加痴呆发生风险的研究现状

林素娜 厉有名

中国临床药理学杂志2017,Vol.33Issue(9):849-852,4.
中国临床药理学杂志2017,Vol.33Issue(9):849-852,4.DOI:10.13699/j.cnki.1001-6821.2017.09.022

长期应用质子泵抑制剂可能增加痴呆发生风险的研究现状

Current situation of progress in long-term use of proton pump inhibitors may increase the risk of dementia

林素娜 1厉有名1

作者信息

  • 1. 浙江大学附属第一医院消化内科,杭州310003
  • 折叠

摘要

Abstract

Proton pump inhibitor (PPI) are one of the most commonly prescribed classes of anti acid drugs,mainly used for peptic ulcer disease,gastroesophageal reflux disease and treatment of Helicobacter pylori.Prolonged use of PPIs is associated with a variety of adverse drug reaction.Also it probably increases the risk of dementia,though its mechanism remains unclear.This article aims to explain the correlation between PPI and dementia and its possible mechanisms.

关键词

质子泵抑制剂/痴呆/认知障碍

Key words

proton pump inhibitor/dementia/cognitive impairment

分类

医药卫生

引用本文复制引用

林素娜,厉有名..长期应用质子泵抑制剂可能增加痴呆发生风险的研究现状[J].中国临床药理学杂志,2017,33(9):849-852,4.

中国临床药理学杂志

OA北大核心CSCDCSTPCD

1001-6821

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