中国全科医学2017，Vol.20Issue(17)：2106-2110,5.DOI:10.3969/j.issn.1007-9572.2017.17.013
贵阳城区40岁及以上居民体质量变化与代谢综合征发病率的随访研究
Relationship between Weight Change and Incidence of Metabolic Syndrome in Guiyang Urban Residents Aged 40 or Over:a 3-year Follow-up Study
摘要
Abstract
Background As weight is strongly related to metabolic syndrome(MS),the association of weight change with the incidence of MS has become one of the focus.Objective To investigate the association between weight change and the incidence of MS based on a 3-year follow-up study of the community residents.Methods This study was conducted from 2011 to 2014.The participants enrolled in this study were 5 850 Guiyang urban residents who aged 40 or over and participated in the "Risk Evaluation of Tumor in Patients with Type 2 Diabetes in China:an Epidemiological Study" conducted in 2011.The participants′ height,weight,waist circumference and blood pressure were measured,and the values of fasting plasma glucose(FPG),high-density lipoprotein cholesterol(HDL-C) and triglyceride(TG) of them were measured as well.We measured the above indicators of them again in December 2014 and those with MS were diagnosed.According to the weight changes during the follow-up,the participants were divided into 5 groups,the weight loss(WL) group(loss≥1.0 kg),weight stable(WS) group(change <1.0 kg),weight gain(WG)-A group(gain 1.0-<2.5 kg),WG-B group(gain 2.5-<5.0 kg),WG-C group(gain ≥5.0 kg).Results A total of 4 392 participants completed the follow-up,with a lost follow-up rate of 24.92%.Of them,males had a lower incidence of MS than females did〔15.87%(223/1 405) vs.27.18%(812/2 987),x2=55.293,P<0.05〕.The incidence of MS increased with the increase of weight in each gender(P<0.05).There were significant differences in the changes of BMI,waist circumference and waist-to-height ratio among each group of the males during the follow-up(P<0.05).Significant differences in the changes of BMI,waist circumference,waist-to-height ratio,SBP and DBP were found among each group of the females during the follow-up(P<0.05).After adjusting for baseline age,BMI,waist circumference,SBP,DBP,FPG,HDL-C,and TG levels,multivariate Logistic regression analysis showed that,compared with WS group of males,the WL group had a lower risk of MS 〔OR=0.411,95%CI(0.262,0.645)〕,while those in the WG-B group〔OR=2.735,95%CI(1.664,4.497)〕 and WG-C group〔OR=3.755,95%CI(1.907,7.395)〕 showed a higher risk of MS;compared with the WS group of females,the WL group showed a lower risk of MS〔OR=0.675,95%CI(0.534,0.854)〕,while those in the WG-A group〔OR=1.446,95%CI(1.125,1.859)〕,WG-B group〔OR=1.778,95%CI(1.355,2.331)〕,and WG-C group〔OR=2.801,95%CI(1.975,3.972)〕 showed a higher risk of MS(P<0.05).Conclusion In Guiyang urban residents who aged 40 or over,females had a higher incidence of MS than males did,and weight gain was the significant risk factor of MS.Weight gain was more closely associated with the incidence of MS in males than in females.关键词
代谢综合征X/体重增长/发病率/人体质量指数Key words
Metabolic syndrome X/Weight gain/Incidence/Body mass index分类
医药卫生引用本文复制引用
袁新,李红,时立新,张巧,彭年春,胡颖..贵阳城区40岁及以上居民体质量变化与代谢综合征发病率的随访研究[J].中国全科医学,2017,20(17):2106-2110,5.基金项目
贵州省科技计划课题(黔科合LG字[2012]039号) （黔科合LG字[2012]039号）
