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组织胶联合聚桂醇急诊内镜下注射治疗食管胃底静脉曲张破裂后出血预后因素分析

刁云辉 贺东黎 戴兵 王祟奇

中国现代医学杂志2017,Vol.27Issue(11):117-121,5.
中国现代医学杂志2017,Vol.27Issue(11):117-121,5.DOI:10.3969/j.issn.1005-8982.2017.11.025

组织胶联合聚桂醇急诊内镜下注射治疗食管胃底静脉曲张破裂后出血预后因素分析

Analysis of prognostic factors in patients with esophageal and gastric varices bleeding after endoscopic injection of tissue adhesive combined with polidocanol

刁云辉 1贺东黎 1戴兵 2王祟奇1

作者信息

  • 1. 河南省南阳市中心医院消化内科1病区,河南 南阳 473009
  • 2. 河南省南阳市中心医院普通外科肝脏病区,河南 南阳 473009
  • 折叠

摘要

Abstract

Objective To investigate the prognostic factors of esophageal gastric varices bleeding after endoscopic injection of tissue adhesive combined with polidocanol. Methods 132 cases with esophageal and gastric varices bleeding were retrospectively analyzed. The recurrent bleeding rate was statistically analyzed. According to bleeding or not, patients were divided into observation group and control group. The influencing factors were analyzed. Results The percentage of patients with INR > 1.5 and RVD <8.5 mm, MELD score, FIB4 score, PT and TB were significantly higher in the observation group than those in the control group (χ2=6.693 and 21.827, P=0.028 and 0.000; t=7.217, 32.041, 11.674 and 7.554, P=0.026, 0.000, 0.000, 0.000 and 0.026), while serum sodium and serum albumin were significantly lower than those in control group (t=16.043, 15.271, P=0.000). Logistic regression analysis showed that INR >1.5, MELD score, FIB4 score and PT were independent risk factors for rebleeding after treatment with tissue glue and polidocanol. RVD >8.5 mm, serum sodium and serum albumin were prognostic factors. Conclusions Further deterioration of liver function and coagulation dysfunction may be the influencing factors in the treatment of patients with GOV.

关键词

食管胃底静脉曲张/组织胶/聚桂醇/再出血/预后

Key words

esophageal varices/tissue glue/polidocanol/rebleeding/prognosis

分类

医药卫生

引用本文复制引用

刁云辉,贺东黎,戴兵,王祟奇..组织胶联合聚桂醇急诊内镜下注射治疗食管胃底静脉曲张破裂后出血预后因素分析[J].中国现代医学杂志,2017,27(11):117-121,5.

中国现代医学杂志

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1005-8982

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