中国现代医学杂志2017，Vol.27Issue(12)：96-100,5.DOI:10.3969/j.issn.1005-8982.2017.12.020
重症急性胰腺炎多重耐药菌铜绿假单胞菌感染的危险因素分析
Risk factors and drug resistance analysis of multi-drug resistance Pseudomonas aeruginosa infection in severe acute pancreatitis*
摘要
Abstract
Objective To analyze the risk factors of Pseudomonas aeruginosa (PAE) infection in severe acute pancreatitis (SAP) patients. Methods Totally 102 patients diagnosed with SAP from January 2006 to December 2016 in our hospital were retrospectively reviewed. And the patients were divided into infection group (17 cases) and control group (85 cases) according to whether or not they were complicated with PAE infection. Risk factors of PAE infection were analyzed through logistic regression analysis. Results The propor-tion of PAE infection in the SAP patients in our hospital was 16.67%. There was no significant difference in gender, etiology or complication between the two groups (P>0.05). However, compared with the control group, the infection group showed older age, higher CT severity index (CTSI) and SAP severity grading, higher inci-dences of ARDS and shock, higher APACHE Ⅱ score and longer ICU stay (P<0.05). Multivariate logistic regression analysis revealed that the risk factors of PAE infection included higher CTSI and APACHE Ⅱscore, higher SAP severity, ARDS occurrence in the acute phase, and prolonged ICU and hospital stay (P<0.05). In the aspect of clinical outcomes, the infection group showed higher incidences of shock and sepsis, longer ICU stay and total hospital stay than the control group (P<0.05); however, no significant difference was found in mortality between the two groups (P>0.05). Conclusions Risk factors of PAE infection include higher CTSI, higher SAP severity, occurrence of ARDS in the acute phase, prolonged ICU and hospital stay, and higher APACHE Ⅱ score at admission.关键词
重症急性胰腺炎/铜绿假单胞菌/危险因素/预后Key words
severe acute pancreatitis/Pseudomonas aeruginosa/risk factor/clinical outcome分类
医药卫生引用本文复制引用
曹春宇,金海,汤武亨,陈园,庄一渝..重症急性胰腺炎多重耐药菌铜绿假单胞菌感染的危险因素分析[J].中国现代医学杂志,2017,27(12):96-100,5.基金项目
2015年浙江省医药卫生一般研究计划(No:2015KYA128) （No:2015KYA128）
