中国医学装备2017，Vol.14Issue(6)：65-68,4.DOI:10.3969/J.ISSN.1672-8270.2017.06.019
螺旋断层放射治疗系统根治性放射治疗29例寡转移非小细胞肺癌的临床效果研究
Research on clinical effect of on the radical radiotherapy for 29 cases with non-small cell lung cancer of oligometastasis
胡小龙 1李宏奇 1刘鹤飞 1徐向生 1吴伟章 1夏廷毅 1王颖杰1
作者信息
- 1. 空军总医院肿瘤放疗科 北京 100142
- 折叠
摘要
Abstract
Objective:To research the curative effect and adverse reaction of using helical tomotherapy (TOMO) on the radical radiotherapy for primary lesion and all of metastases of patients with non-small cell lung cancer of oligometastasis.Methods: 29 patients with NSCLC of oligometastasis (the number of metastases≤5) in initial treatment were enrolled in this retrospective analysis. The primary lesion and all of metastases were taken radical radiotherapy by using TOMO system, and the average and median of biological effective dose (BED10) 95Gy and 94Gy, respectively, and the number of neutral position chemotherapy period was 4.Results: In 30 months of neutral position follow-up visit, the total effective rate of lesion treatment in short-term curative effect was 80%, and the survival rates after 1, 2 and 3 years, respectively, were 52%,17% and 7%. The median survival time was 30 months, the progression-free survivals were 52%, 17% and 7% after 1, 2 and 3 years, and the median progression-free time was 12 months. The adverse reactions of most patients were 1-2th degree, and only a few patients were 3th degree. And the 4th degree of adverse reaction or the death related with treatment hadn't were found.Conclusions: Based on systematic therapy for non-small cell lung cancer of oligometastasis, the radical radiotherapy of primary lesion and all metastases can obviously improve patients' overall survival and progression-free survival, at the same time, its adverse reaction is durable during treatment.关键词
非小细胞肺癌/寡转移/根治性放射治疗/螺旋断层放射治疗系统Key words
Non-small cell lung cancer/Oligometastasis/Radical Radiotherapy/Tomotherapy (TOMO)分类
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胡小龙,李宏奇,刘鹤飞,徐向生,吴伟章,夏廷毅,王颖杰..螺旋断层放射治疗系统根治性放射治疗29例寡转移非小细胞肺癌的临床效果研究[J].中国医学装备,2017,14(6):65-68,4.
