摘要
Abstract
Objective:To compare the clinical efficacy of percutaneous radiofrequency ablation (RFA) under ultrasound guidance and high power microwave ablation (MWA) in the treatment of intermediated or advanced-staged primary liver cancer.Methods: 60 patients with primary liver cancer who were in accordance with the inclusion criteria were divided into radiofrequency ablation group (RFA group, 30 cases) and microwave ablation group (MWA group, 30 cases). A series indicators, such as postoperative complete remission rate of lesion, 1 year survival rate, 1 year progression-free survival rate, postoperative adverse reaction and postoperative complication, for these patients of two groups were compared and analyzed.Results:The total complete remission rate of the RAF group and the MWA group were 66.7% and 76.7%, respectively, and the difference between them was significant (x2=3.776, P<0.05). When the lesion was larger than 5 cm, the complete remission rate of RFA group and MWA group were 41.7% and 63.6%, respectively, and the difference between them was significant (x2=4.231,P<0.05). When the lesion was between in 3-5 cm, the complete remission rate of RFA group and MWA group were 75.0% and 81.2%, respectively, while the difference between them was no significant (x2=0.976,P>0.05). For postoperative complication, there were 3 cases in RAF group while there were 5 cases in MWA group, and the difference between them was significant (x2=3.373, P<0.05). There was no death case that was related with treatment in the two postoperative groups. The 1 year survival rate and 1 year progression-free survival rate of RAF group were 90.0% and 53.3%, respectively, and that of MWA group were 86.7% and 60.0%, and the difference between them was no significant (x2=0.877,P>0.05).Conclusion: For intermediated or advanced-staged primary liver cancer with the larger or multiple lesions, complete remission rate of high-power MWA group is better than that of RAF. But there was no significant difference for 1 year total survival rate and 1 year progression-free survival rate between the two groups, respectively. And the postoperative adverse reaction of high-power MWA group was higher than that of RAF group.关键词
原发性肝癌/射频消融/微波消融/疗效/超声引导Key words
Primary liver cancer/Radiofrequency ablation/Microwave ablation/Curative effect/Ultrasound guidance分类
医药卫生
