中国药业2017，Vol.26Issue(9)：53-55,3.DOI:10.3969/j.issn.1006-4931.2017.07.017
尼莫地平联合氟桂利嗪治疗偏头痛临床评价
Clinical Evaluation of Nimodipine Combined with Flunarizine in Treating Migraine
赵英兵 1聂元文 1徐甜颖1
作者信息
- 1. 牡丹江医学院第二附属医院,黑龙江牡丹江 157000
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of Nimodipine combined with Flunarizine in treating migraine. Methods Totally 48 patients with migraine admitted to our hospital from April 2015 to October 2016 were randomly divided into two groups. 24 cases in each group. The single prodrug group was treated with Nimodipine. on this basis. the combined drug group was added Flunarizine. The clinical efficacy. the onset of disease. the degree of pain. the difference in the index of blood rheology and the adverse drug reactions of the two groups were compared. Results The total efficiency rate of the combined drug group was 95. 83%. which was significantly higher than 75. 00% of the single prodrug group ( P < 0. 05 ) . Before treatment. the onset of disease. degree of pain in the two groups showed no significant difference ( P > 0. 05 ) . but those improved more significantly in the combined drug group after treatment ( P <0. 05 ) . Before treatment. the index of blood rheology in the two groups showed no significant difference ( P > 0. 05 ) . but that improved more significantly in the combined drug group after treatment ( P < 0. 05 ) . There was no serious adverse drug reaction occurred in the two groups. Conclusion Nimodipine combined with Flunarizine in treating migraine disease has good clinical curative effect. can effec-tively improve the index of blood rheology. control seizures. and relieve the pain of patients without obvious adverse drug reaction. it is safety and worthy of clinical promotion.关键词
尼莫地平/氟桂利嗪/偏头痛/临床疗效Key words
Nimodipine/Flunarizine/migraine/clinical effect分类
医药卫生引用本文复制引用
赵英兵,聂元文,徐甜颖..尼莫地平联合氟桂利嗪治疗偏头痛临床评价[J].中国药业,2017,26(9):53-55,3.
