中国药业2017，Vol.26Issue(10)：27-30,4.DOI:10.3969/j.issn.1006-4931.2017.10.007
壮药清解雾化液质量标准研究
Quality Standard of Qingjie Atomized Liquid
摘要
Abstract
Objective To establish the quality standard of Qingjie Atomized Liquid. Methods The Morus Alba,Emilia Sonchifolia and Radix Ilicis Asprellae in the Qingjie Atomized Liquid were identified by thin layer chromatography(TLC). The content of rutin in the Qingjie Atomized Liquid was determined by high performance liquid chromatography(HPLC). The column was Discovery C18 column (250 mm × 4. 6 mm,5 μm)with mobile phase of methanol-0. 1% phosphoric acid solution(35 :65),the detection wavelength was 356 nm,the flow rate was 1. 0 mL/min,the column temperature was 35 ℃. Results The TLC spots of Morus Alba,Emilia Sonchifolia and Radix Ilicis Asprellae were clear and showed negative control without interference. The concentration of rutin is linear in the range of 2-20 g/mL and had a good linear relationship with the peak area,r=0. 9996,the average recovery was 99. 92%,RSD was 0. 99%(n=6). Conclusion The method is simple,specific and reproducible,which can be used for the quality control of Qingjie Atomized Liquid.关键词
清解雾化液/质量标准/薄层色谱法/高效液相色谱法/芦丁Key words
Qingjie Atomized Liquid/quality standard/TLC/HPLC/rutin分类
医药卫生引用本文复制引用
莫小林,伍小燕,龚敏阳,陈晓明,韦振源..壮药清解雾化液质量标准研究[J].中国药业,2017,26(10):27-30,4.基金项目
广西壮族自治区卫生厅中医药科技专项制剂类课题资助项目和医院制剂遴选课题 [ GZYZ1104 ] （）
全国中药特色技术传承人才培训项目[ J20164811007 ]. （）
