摘要
Abstract
Objective To investigate the application value of Paishi decoction combined with tamsulosin af-ter holmium laser lithotripsy of ureteral calculi. Methods Ninety-eight cases with ureteral calculi were divid-ed into the observation group and the control group according to the method of random number table (49 cases in each group). Both groups were treated with holmium laser lithotripsy. After operation, the observation group was treated with Paishi decoction combined with tamsulosin while the control group was treated with tamsulosin alone. The clearance rates of stone, 24 h urine biochemical indexes before and after treatment, incidence rates of infection and renal colic, length of hospital stay, hospitalization costs and incidence of adverse reactions were compared between the two groups at the first and second weeks. Results At the first and second weeks after operation, the clearance rates of stones in the observation group (81.6%, 100%) were higher than control group (P<0.05). After treatment, the levels of 24 h urine Ca2+, uric acid and urine oxalate were decreased, and the levels in observation group [(3.31±1.17) mmol/24 h, (2.84±0.97) mmol/24 h, (0.22±0.08) mmol/24 h] were signifi-cantly lower than those in control group (P<0.05). The incidence of renal colic in the observation group (10.2%) was significantly lower than that in the con-trol group (26.5%) (P<0.05). The length of hospital stay and hospitalization costs of observation group[(6.2±2.5) d, (4167.6±344.1) yuan] were less than control group (P<0.05). The incidence rates of adverse reac-tions showed no significant differences. Conclusion The application of holmium laser lithotripsy combined with Paishi decoction and tamsulosin can avoid residual stones, accelerate the removal of ureteral calculi and im-prove 24h urine biochemical indexes in patients. The hospitalization costs is little, and safety and economy are satisfactory.关键词
输尿管结石/钬激光术/排石汤/坦索罗辛Key words
Ureteral calculi/holmium laser lithotripsy/Paishi Decoction/tamsulosin分类
医药卫生