中国中医药信息杂志2017，Vol.24Issue(7)：19-22,4.DOI:10.3969/j.issn.1005-5304.2017.07.005
443例原发性高血压中医证型分布及血压变异性规律研究
Study on TCM Syndrome Distribution and Blood Pressure Variability in 443 Patients with Primary Hypertension
摘要
Abstract
Objective To study the TCM syndrome distribution and the laws of blood pressure variability in patients with primary hypertension.Methods Totally 443 patients with primary hypertension were selected; four diagnostic data were collected to conduct syndrome differentiation (main syndrome was chosen for compound syndrome); 24 h ambulatory blood pressure was monitored and blood pressure variability of each syndrome was compared.Results Among 443 cases of patients, liver-kidney yin deficiency syndrome (157 cases) > qi yin deficiency syndrome (83 cases) > yang deficiency syndrome (76 cases) > phlegm dampness syndrome (65 cases) > liver yang hyperactivity syndrome (62 cases). There was statistical significance in ages of different syndromes, but there was no statistical significance in gender, family history and course of disease (P>0.05). Compared with liver-kidney yin deficiency syndrome, 24 h systolic blood pressure and 24 h mean blood pressure of phlegm dampness syndrome were significantly different (P<0.05); circadian rhythm abnormality rates of liver-kidney yin deficiency syndrome, liver yang hyperactivity syndrome, qi yin deficiency syndrome, phlegm dampness syndrome and yang deficiency syndrome were 80.85% (38/47), 66.67% (14/21) ,81.48% (22/27), 86.96% (20/23), and 78.79% (26/33), respectively, without statistical significance in different syndromes (χ2=3.031,P=0.553).Conclusion Among the 443 hypertensive patients, patients with liver-kidney yin deficiency syndrome were the most, and patients with liveryang hyperactivity syndrome were the least. Phlegm dampness syndrome has the highest blood pressure, while liveryang hyperactivity syndrome has the lowest blood pressure. Patients with liver-kidney yin deficiency syndrome are with the highest blood pressure variability, while patients with qi yin deficiency syndrome are with the lowest blood pressure variability.关键词
高血压/中医证型/血压变异性/动态血压Key words
hypertension/TCM syndromes/blood pressure variability/ambulatory blood pressure分类
医药卫生引用本文复制引用
鲁成,宋磊,刘永明..443例原发性高血压中医证型分布及血压变异性规律研究[J].中国中医药信息杂志,2017,24(7):19-22,4.基金项目
国家自然科学基金(81102671) （81102671）
上海市高级中西医结合人才培养项目(ZYSNXD012-RC-ZXY002) （ZYSNXD012-RC-ZXY002）
上海市卫生局课题(20134153) （20134153）
上海市中医药事业发展三年行动计划(ZY3-JSFC-2-1033) （ZY3-JSFC-2-1033）
