中国中医药信息杂志2017，Vol.24Issue(7)：32-35,4.DOI:10.3969/j.issn.1005-5304.2017.07.008
针刺治疗对缺血性脑卒中患者静息态功能磁共振的影响
Effects of Acupuncture Therapy on Resting State Functional Magnetic Resonance Imaging in Patients with Ischemic Stroke
摘要
Abstract
Objective To discuss the effects of acupuncture therapy on resting state functional magnetic resonance imaging (fMRI) in patients with ischemic stroke; To explore the central mechanism of acupuncture therapy.Methods Ten is chemic stroke patients with hemiplegia limbs and ten matched control subjects were included. Treatment group was given anti-platelet aggregation, anticoagulation, and nutrition brain cell therapy. At the same time, acupuncture therapy was given, taking Jianyu, Quchi, Shousanli, Waiguan, Hegu, Zusanli, Fenglong, Yanglingquan, Sanyinjiao, and Taichong, with even reinforcing-reducing method, and retaining the needle 30 min, manipulating needle every 10 min, once a day, 5 times a week, needle stopping for 2 d, for continuous 30 d. The health group did not undergo any treatment. BOLD-fMRI imaging technique was used, and based on RSET1.8 software, the parameters of brain activity before and after treatment were observed by amplitude of low frequency fluctuation (ALFF) method. The Results were compared with healthy group. Results Before treatment, the ALFF value of left caudate nucleus, putamen and globus pallidus in the treatment group was lower than that in the health group, and the ALFF value of bilateral precentral and postcentral gyrus, left grus frontalis superior, gyrus frontalis medius, gyrus temporalis medius and precuneus was higher than the health group (P<0.05). After treatment, the ALFF value in left caudate nucleus, putamen and globus pallidus in the treatment group was higher than that before treatment, and the ALFF value in left gyrus frontalis superior, gyrus frontalis medius and precuneus decreased than before group (P<0.05).Conclusion In the resting state of the ischemic stroke patients with hemiplegia limbs, the principal injured brain regions are caudate nucleus, putamen and globus pallidus. Acupuncture has a regulatory role for these brain areas, presumably may be the central mechanism of efficacy.关键词
针刺/缺血性脑卒中/低频振幅/静息态功能磁共振Key words
acupuncture/ischemic stroke/ALFF/resting state functional magnetic resonance imaging分类
医药卫生引用本文复制引用
丁彩霞,胡丹,张兰坤,李传游,姜寒,张晓浩,盛蕾..针刺治疗对缺血性脑卒中患者静息态功能磁共振的影响[J].中国中医药信息杂志,2017,24(7):32-35,4.基金项目
江苏省中医药管理局支撑项目(LZ13094) （LZ13094）
