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多指标正交试验优化理冲生髓饮的醇提工艺

王艳宏 赵娟萍 尚冬雪 赵雪 田苗 韩凤娟

中国中医药信息杂志2017,Vol.24Issue(7):76-80,5.
中国中医药信息杂志2017,Vol.24Issue(7):76-80,5.DOI:10.3969/j.issn.1005-5304.2017.07.018

多指标正交试验优化理冲生髓饮的醇提工艺

Optimization of Ethanol Extraction Technology ofLichong ShengsuiDecoction by Multi-index Orthogonal Test

王艳宏 1赵娟萍 1尚冬雪 1赵雪 1田苗 2韩凤娟2

作者信息

  • 1. 黑龙江中医药大学药学院,黑龙江哈尔滨 150040
  • 2. 黑龙江中医药大学附属第一医院,黑龙江哈尔滨 150040
  • 折叠

摘要

Abstract

Objective To optimize the ethanol extraction technology ofLichong ShengsuiDecoction.Methods An L9(34) orthogonal test was used in the study. The extraction rates of calycosin glycoside, icariin, baohuosideⅠ, ginsenoside Rg1, ginsenoside Re, ginsenoside Rb1, astragaloside, and ginsenoside Rd were set as indexes. The influence of ethanol concentration, extraction time, extraction temperature, and amount of ethanol on the yield of Lichong ShengsuiDecoction were detected by comprehensive scoring method.Results The optimal ethanol extraction technology forLichong ShengsuiDecoction was soaking for 2 h with ten times of 60% ethanol and then reflux extracting for two times; extraction time was 1.5 h each time at 80℃.ConclusionThe optimal extraction technology is efficient, stable and feasible, which can provides data for the further study ofLichong ShengsuiDecoction.

关键词

理冲生髓饮/正交试验/多指标/醇提工艺

Key words

Lichong ShengsuiDecoction/orthogonal test/multi-index/ethanol extraction technology

分类

医药卫生

引用本文复制引用

王艳宏,赵娟萍,尚冬雪,赵雪,田苗,韩凤娟..多指标正交试验优化理冲生髓饮的醇提工艺[J].中国中医药信息杂志,2017,24(7):76-80,5.

基金项目

国家自然科学基金(81273788、81473717) (81273788、81473717)

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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