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PI-IBS与NPI-IBS患者的临床对比研究

张小平 潘红芳 潘良 旬兰兰

重庆医学2017,Vol.46Issue(9):1206-1207,1210,3.
重庆医学2017,Vol.46Issue(9):1206-1207,1210,3.DOI:10.3969/j.issn.1671-8348.2017.09.018

PI-IBS与NPI-IBS患者的临床对比研究

Clinical comparative study of patients with PI-IBS and NPI-IBS

张小平 1潘红芳 1潘良 1旬兰兰1

作者信息

  • 1. 江苏省常州市金坛区人民医院消化科 213200
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摘要

Abstract

Objective To observe the clinical characteristics in the patients with post infectious irritable bowel syndrome(PI-IBS) and patients with non-PI-IBS(NPI-IBS).Methods Ninety-three patients with irritable bowel syndrome(IBS) treated in our hospital from March 2014 to June 2015 were selected,including 38 cases of PI-IBS and 55 cases of NPI-IBS.The differences of serum inflammatory cytokines levels,gastrointestinal score and gastrointestinal function were compared between the two groups.Resuits The levels of CRP,IL-18 and IL-6 in the PI-IBS group were significantly higher than those in the NPI-IBS group,and the difference was statistically significant (P<0.05);the level of GAS,VIP and MOT in the PI-IBS group were significantly lower than those in the NPI-IBS group,the difference was statistically significant(P<0.05);the bowel sounds score,abdominal distension and pain score and gastrointestinal reaction score in the PI-IBS group were obviously higher than those in the NPI-IBS group,the difference was statistical significance (P<0.05);the various dimensional scores of quality of life in the PI-IBS group were lower than those in the NPI-IBS group,and the difference was statistically significant (P<0.05).Conclusion The levels of serum inflammatory cytokines in PI-IBS patients are higher,moreover the gastrointestinal function is poorer than that in NPI-IBS patients,which can be the indicators of clinical differentiation.

关键词

肠易激综合征/炎症诱导/细胞因子类/胃肠功能

Key words

irritable bowel syndrome/inflammatory induction/cytokines/gastrointestinal function

分类

医药卫生

引用本文复制引用

张小平,潘红芳,潘良,旬兰兰..PI-IBS与NPI-IBS患者的临床对比研究[J].重庆医学,2017,46(9):1206-1207,1210,3.

重庆医学

1671-8348

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