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基质金属蛋白酶-2、9与脑梗死初发及复发相关性研究

喻明 杨小芳 聂本刚

中国实用神经疾病杂志2016,Vol.19Issue(5):18-19,2.
中国实用神经疾病杂志2016,Vol.19Issue(5):18-19,2.

基质金属蛋白酶-2、9与脑梗死初发及复发相关性研究

The correlation analysis of serum matrix metalloproteinase-2, 9 and primary, recurrent cerebral infarction

喻明 1杨小芳 1聂本刚1

作者信息

  • 1. 四川遂宁市中心医院神经内科 遂宁 629000
  • 折叠

摘要

Abstract

Objective To explore the levels of serum matrix metalloproteinase-2,9 (MMP-2,9) in primary and recurrent cerebral infarction patients.Methods We selected 343 cases with primary cerebral infarction as primary group and 307 cases with recurrent cerebral infarction as recurrent group and 320 healthy controls as control group.Then the levels of serum MMP -2,9 of three groups were tested.Results The levels of serum MMP-2,9 in recurrent group were significantly higher than that in primary group,and primary group had higher levels relative to control group (P<0.05).And the expressions of MMP -2 were not correlative to MMP-9 in both primary and recurrent groups (P>0.05).Conclusion MMP-2 and MMP-9 play an important role in the development of cerebral infarction and monitor cerebral infarction recurrence as a molecular marker.

关键词

基质金属蛋白酶-2/基质金属蛋白酶-9/脑梗死

Key words

Metalloproteinase-2/Metalloproteinase-9/Cerebral infarction

分类

医药卫生

引用本文复制引用

喻明,杨小芳,聂本刚..基质金属蛋白酶-2、9与脑梗死初发及复发相关性研究[J].中国实用神经疾病杂志,2016,19(5):18-19,2.

中国实用神经疾病杂志

1673-5110

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