中国实用神经疾病杂志2016，Vol.19Issue(6)：4-5,2.
原发性癫痫合并阻塞性睡眠呼吸暂停低通气综合征的临床特点
Clinical features of obstructive sleep apnea hypopnea syndrome in patients with idiopathic epilepsy
摘要
Abstract
Objective To investigate the clinical characteristics of obstructive sleep apnea hypopnea syndrome(OSAHS) in patients with epilepsy.Methods Clinical data(mainly including history,polysomnography,therapy and follow-up visits) of 16 idiopathic epilepsy cases with OSAHS admitted to our hospital from June 2007 to June 2014 were analyzed retrospectively.Results Of all the 16 cases,generalized tonic-clonic seizures occurred in 13 cases and partial seizures in 3 cases,11 cases happened at night and 5 cases happened in the daytime.Of all patients diagnosed as OSAHS by the monitor of polysomnography,there were 4 severe OSAHS,4 moderate OSAHS and 3 mild OSAHS.Patients with severe OSAHS still repeated seizures after the treatment of simple antiepileptic drugs,but the frequency of seizures decreased in 3 cases and the seizure ceased in 1 case for six months to 3 years follow-up when patients were treated by sodium volproate and continuous positive airway pressure (CPAP).Conclusion OSAHS with epilepsy is much common in middle-aged males.And the main type of seizure is generalized tonic-clonic seizure which usually occurs at night.For patients with worse effect treated by single antiepileptic drug,the combined treatment of antiepileptic drugs and CPAP is more effective.关键词
原发性癫痫/阻塞性睡眠呼吸暂停低通气综合征/临床特点Key words
Epilepsy/Obstructive sleep apnea hypopnea syndrome/Clinical feature分类
医药卫生引用本文复制引用
项正兵,屈新辉,谢旭芳,吴晓牧..原发性癫痫合并阻塞性睡眠呼吸暂停低通气综合征的临床特点[J].中国实用神经疾病杂志,2016,19(6):4-5,2.基金项目
国家临床重点专科建设项目(卫办医政函[2012]649号) （卫办医政函[2012]649号）
