中国实用神经疾病杂志2016，Vol.19Issue(6)：9-11,3.
美洛西林钠与头孢哌酮舒巴坦治疗早发性脑卒中相关性肺炎的疗效及安全性比较
Comparative analysis of safety and efficacy of mezlocillin sodium VS cefoperazone sulbactam in the treatment of early-onset cerebral stroke-associated pneumonia
刘瑞 1刘艳芬1
作者信息
- 1. 陕西延安市人民医院药剂科 延安 716000
- 折叠
摘要
Abstract
Objective To observe the safety and efficacy between mezlocillin sodium and cefoperazone sulbactam in earlyonset stroke-associated pneumonia patients(EOP).Methods Eighty cases with EOP from January 2010 to January 2015 in our hospital were randomly divided into observation group and control group.Patients in the observation group received mezlocillin sodium,the control group received cefoperazone sulbactam.Then the clinical curative effect and safety between two groups were comparatively analyzed.Results In terms of total effective rate,the significant efficiency rate and the bacterial clearance rate,no significant differences were found between the observation group and the control group(P＞0.05).After treatment,the observation group had significantly lower detection rate of Acinetobacter than the control group,while as for laboratory indexes such as blood cell count,procalcitonin,C-reactive protein,the observation group was obviously prior to the control group(P＜ 0.05).Conclusion Not only mezlocillin sodium but also cefoperazone sulbactam has a good clinical curative effect and bacterial clearance rate in the treatment of EOP.Mezlocillin sodium takes an advantage over cefoperazone sulbactam concerning improving the inflammatory response and has lower detection rate of multiple-drug resistant bacteria,thus which has better safety in clinical application.关键词
脑卒中相关性肺炎/美洛西林钠/头胞哌酮舒巴坦Key words
Cerebral stroke-associated Pneumonia/Mezlocillin sodium/Cefoperazone sulbactam分类
医药卫生引用本文复制引用
刘瑞,刘艳芬..美洛西林钠与头孢哌酮舒巴坦治疗早发性脑卒中相关性肺炎的疗效及安全性比较[J].中国实用神经疾病杂志,2016,19(6):9-11,3.
