解放军医学杂志2017，Vol.42Issue(2)：144-148,5.DOI:10.11855/j.issn.0577-7402.2017.02.10
性别对急性ST段抬高型心肌梗死患者再灌注时间延迟的影响
Analysis of reperfusion delay in patients with acute ST elevated myocardial infarction based on gender difference
张中 1饶萌萌 1毛帅 1王守力 1赵蓓 1魏腾飞 1刘佩林 1刘利峰 1刘莉 1赵京涛 1时全星 1殷召1
作者信息
- 1. 100101北京 解放军306医院心内科
- 折叠
摘要
Abstract
Objective To examine the influence of gender difference on the reperfusion delay in patients with ST-elevation myocardial infarction (STEMI).Methods A total of consecutive 325 patients with STEMI were analyzed admitted in the 306 Hospital of PLA from Jan.2011 to Dec.2015.Patients were divided into two groups:male group (n=268) and female group (n=57).The clinical data and the time intervals including symptom onset to first medical contact (So-to-FMC),transfer delay (FMC-to-D),FMC to balloon dilatation (FMC-to-B),activation delay and door to balloon (D-to-B) time were compared between different gender groups,and the prognosis was observed.Results The overall median of pre-hospital delay was 125 minutes.The median of prehospital delay time (male 119.5min vs.female 160.0min) and So-to-FMC time (male 69.5min vs.female 100.0min) were longer in female than in male patients,but no statistical difference existed (P＞0.05) between the two groups in pre-hospital delay,So-to-FMC,FMC-to-B,D-to-B and total ischemia time.Compared with male patients,female patients were more likely to have additional comorbidities,such as hypertension and diabetes mellitus,and lower rate of smoking (P＜0.05).However,the incidence of major adverse cardiac and cerebrovascular events (MACCE) showed no significant difference between female and male patients at 30-day (male 5.22％ vs.female 5.26％) and I-year (male 10.82％ vs.female 8.77％) follow-up (P＞0.05).Conclusion The influence of gender on reperfusion delay is gradually weakening.关键词
心肌梗死/性别因素/再灌注延迟Key words
myocardial infarction/sex factors/reperfusion delay分类
医药卫生引用本文复制引用
张中,饶萌萌,毛帅,王守力,赵蓓,魏腾飞,刘佩林,刘利峰,刘莉,赵京涛,时全星,殷召..性别对急性ST段抬高型心肌梗死患者再灌注时间延迟的影响[J].解放军医学杂志,2017,42(2):144-148,5.
