农业生物技术学报2017，Vol.25Issue(3)：502-510,9.DOI:10.3969/j.issn.1674-7968.2017.03.017
基于非酶杂交链式反应的生物传感器研究进展
Research Progress in the Hybridization Chain Reaction Based Biosensor
摘要
Abstract
Hybridization chain reaction (HCR) is a kind of self-assembly reaction which can be carried out without enzyme participation at room temperature.It is a new type of signal amplification method.It is not only widely used in the common areas,such as colorimetric,fluorescent and electrochemical method,but also in the new field of Chemiluminescence,Electrochemical luminescence,Photochemiluminescence and Raman spectra and so on.So biosensor based on HCR can be used to detect nucleic acids,proteins,cells,small molecules and other biological molecules.This paper reviews the application of the HCR-based biosensors in the biosensing field in the nearly four years,and the future development trend is prospected.关键词
杂交链式反应/生物传感器/快速检测/生物分子Key words
Hybridization chain reaction/Biosensor/Rapid detection/Biological molecules分类
农业科技引用本文复制引用
邵向丽,朱龙佼,周忻,许文涛..基于非酶杂交链式反应的生物传感器研究进展[J].农业生物技术学报,2017,25(3):502-510,9.基金项目
国家自然科学基金(No.31671922) （No.31671922）
