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2-(2-呋喃甲酰氨基)苯并噻唑的合成及其抑菌活性研究

高扬 杨建 高素美 王雪松 唐孝荣

西华大学学报(自然科学版)2016,Vol.35Issue(6):92-96,5.
西华大学学报(自然科学版)2016,Vol.35Issue(6):92-96,5.DOI:10.3969/j.issn.1673-159X.2016.06.019

2-(2-呋喃甲酰氨基)苯并噻唑的合成及其抑菌活性研究

Synthesis of N-(benzo [d] thiazol-2-yl) furan-2-carboxamide and Research on Its Antifungal Activity

高扬 1杨建 1高素美 1王雪松 1唐孝荣1

作者信息

  • 1. 西华大学理学院,四川成都610039
  • 折叠

摘要

Abstract

A new heterocyclic amide derivative N-(benzo[d] thiazol-2-yl) furan-2-carboxamide was synthesized according to the principle of bioactive substructure combination using furan-2-carboxylic acid and 2-amino-benzothiazole as raw materials,and its antifungal activity against five plant pathogenic fungi (Rhizoctonia solani,Botrytis cinema,Gibberella zeae,Helminthosporium maydis and Sclerotinia sclerotiorum) was tested.Results show that the synthesized target compound reveals excellent antifungal activity against the five fungi.Among them,its anti-activity against Helminthosporium maydi,Botrytis cinema and Sclerotinia sclerotiorum is better than carbendazim.Meanwhile,its structure is confirmed by 1H NMR and 13C NMR.

关键词

抑菌活性/杂环酰胺衍生物/植物病原真菌

Key words

antifungal activity/heterocyclic amide derivatives/plant pathogenic fungi

分类

生物科学

引用本文复制引用

高扬,杨建,高素美,王雪松,唐孝荣..2-(2-呋喃甲酰氨基)苯并噻唑的合成及其抑菌活性研究[J].西华大学学报(自然科学版),2016,35(6):92-96,5.

西华大学学报(自然科学版)

OACSTPCD

1673-159X

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