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心脑苏颗粒成型工艺优选

汪铜芳 张咏梅 李姗姗 潘金火 王建春 陈晓峰 蒋志涛

世界中医药2017,Vol.12Issue(2):411-413,3.
世界中医药2017,Vol.12Issue(2):411-413,3.DOI:10.3969/j.issn.1673-7202.2017.02.044

心脑苏颗粒成型工艺优选

Optimization for Formation Process of Xinnaosu Granules

汪铜芳 1张咏梅 2李姗姗 2潘金火 1王建春 2陈晓峰 1蒋志涛2

作者信息

  • 1. 南京中医药大学药学院,南京,2100232
  • 2. 张家港市中医医院江苏省企业研究生工作站,张家港,215600
  • 折叠

摘要

Abstract

Objective:To optimize formation technology of Xinnaosu granules.Methods:A single factor and orthogonal experiment was designed.The particle moisture absorption rate, the forming rate and the repose angle were taken as judging conditions to optimize the type and dosage of auxiliary materials and the concentration of wetting agent.To determine the optimum molding processes conditions.Results:The dextrin was optimized as excipient.Prescription of the clear cream and excipient was set as 1:1 and 90% ethanol was set as wetting agent.The drying temperature was set as 60 degrees centigrade.Conclusion:Xinnaosu Granule prepared by this method has stable properties, excellent appearance, few moisture absorption and good dissolubility.This method can be utilized in industrial manufacture.

关键词

心脑苏颗粒/成型工艺/正交设计

Key words

Xinnaosu granules/Formation technology/Orthogonal design

分类

医药卫生

引用本文复制引用

汪铜芳,张咏梅,李姗姗,潘金火,王建春,陈晓峰,蒋志涛..心脑苏颗粒成型工艺优选[J].世界中医药,2017,12(2):411-413,3.

基金项目

张家港市中医医院青年自然科学基金项目(编号:zzyq1308) (编号:zzyq1308)

世界中医药

OACHSSCDCSTPCD

1673-7202

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