棕榈酸帕利哌酮注射剂与利培酮口服液治疗急性期精神分裂症的临床研究OA北大核心CSCDCSTPCD
Clinical trial of palipiridone palmitate injection and risperidone oral solution in the treatment of acute schizophrenia
目的 观察棕榈酸帕利哌酮治疗急性期精神分裂症的临床疗效、社会功能恢复及安全性.方法 80例急性期精神分裂症患者随机分为对照组40例和试验组40例.对照组口服利培酮口服液4～6 mg·d-1,每日2次;试验组肌内注射棕榈酸帕利哌酮75～150 mg,治疗第1日注射剂量为150 mg,第8日100 mg,第36(±7)日根据病情需要选择剂量为75 ～ 150mg.2组患者均治疗8周.于基线、治疗第1,2,4,8周末分别评定阳性与阴性症状量表(PANS…查看全部>>
Objective To explore the efficacy,social function and safety of paliperidone palmitate in the treatment of acute schizophrenics.Methods A total of 80 patients with acute schizophrenia were randomly divided into treatment group and control group,each group with 40 cases.The control group received 4-6 mg · d-1risperidone oral solution twice a day,while the treatment group was given paliperidone palmitate injection at the dosage of 150 mg on day 1,100 mg on day…查看全部>>
陈杰;宋立平;胡晓华
华中科技大学同济医学院附属精神卫生中心,武汉430022华中科技大学同济医学院附属精神卫生中心,武汉430022华中科技大学同济医学院附属精神卫生中心,武汉430022
医药卫生
棕榈酸帕利哌酮利培酮急性期精神分裂症社会功能
paliperidone palmitaterisperidone oral solutionacute schizophreniasocial function
《中国临床药理学杂志》 2017 (4)
308-311,4
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