中国临床药理学杂志2017，Vol.33Issue(4)：376-380,384,6.DOI:10.13699/j.cnki.1001-6821.2017.04.024
体外膜肺氧合对抗菌药物药代动力学影响的研究进展
Research advance in the effect of extracorporeal membrane oxygenation on the pharmacokinetics of antibacterials
徐思露 1邵华 2胡琳璘 2于锋1
作者信息
- 1. 中国药科大学临床药学教研室,南京210009
- 2. 东南大学附属中大医院药学部,南京210009
- 折叠
摘要
Abstract
Extracorporeal membrane oxygenation(ECMO) is an effective assistant method for the life support on the base of the extracorporeal circulation.ECMO will have an impact on the pharmacokinetics of antibacterials,which changing the plasma concentration of antibacterials in order to affect drug effects.To provide a theoretical basis for the optimization of antibacterial therapy regimens during ECMO treatment,this article described the changes of the pharmacokinetics of antibacterials in critically ill patients receiving ECMO treatment according to the published papers,as well as the correlated mechanism.关键词
体外膜肺氧合/抗菌药物/药代动力学/重症患者Key words
extracorporeal membrane oxygenation/antibacterials/pharmacokinetics/critically ill patients分类
医药卫生引用本文复制引用
徐思露,邵华,胡琳璘,于锋..体外膜肺氧合对抗菌药物药代动力学影响的研究进展[J].中国临床药理学杂志,2017,33(4):376-380,384,6.
