中国全科医学2017，Vol.20Issue(10)：1200-1203,4.DOI:10.3969/j.issn.1007-9572.2017.10.012
臭氧自血疗法辅助治疗男性原发性高血压病的疗效和安全性研究
Efficacy and Safety of Ozoned Autohemotherapy in Adjuvant Therapy of Men with Primary Hypertension
摘要
Abstract
Objective To evaluate the efficacy and safety of ozoned autohemotherapy (O 3-AHT)in adjuvant therapy of men with primary hypertension. Methods Sixty male patients with primary hypertension treated at Xuanwu Hospital Capital Medical University from January 2014 to January 2015 were randomly divided into experiment group and control group by random number table method,each group had 30 cases. The control group orally took levamlodipine at a dose of 5 mg,once per day. Based on that of the control group,adjuvant therapy of O 3-AHT (concentration:20 mg/ L,once per two days,ten times a course of treatment courses)was given to the experiment group. The systolic blood pressure (SBP)and heart rate (HR)before treatment (T 0 ),3 months after the first course of treatment (T 1 ),3 months after the second course of treatment (T 2 ),3 months after the third course of treatment (T 3 )were recorded;the oral status and grades of satisfaction index (PSI)scores of T 3 were recorded. The incidence of adverse events during the treatment was recorded. Results There was no significant difference in age and course of disease (P > 0. 05). There was significant difference in SBP between two groups (P < 0. 05). There was significant difference in SBP at different time points (P < 0. 05). The treatment method and time had interactive effects on SBP (P < 0. 05). There was no significant difference in HR between two groups (P > 0. 05),there was no significant difference in HR at different time points (P > 0. 05). The treatment method and time had no interactive effects on HR (P > 0. 05). The status of taking medicine orally and grades of PSI scores of the experiment group were significantly better than those of the control group (P < 0. 05). None of the patients in the two groups had severe hypotension,cardiovascular and cerebrovascular accident, hemolysis,allergies and other adverse reactions. Conclusion O 3-AHT shows obvious curative effect and high safety in adjuvant therapy of men with primary hypertension.关键词
高血压/臭氧/自血疗法/治疗结果/安全Key words
Hypertension/Ozone/Autohemotherapy/Treatment outcome/Safety分类
医药卫生引用本文复制引用
曹国庆,戴欣钰,赵娜,左欣鹭,倪家骧..臭氧自血疗法辅助治疗男性原发性高血压病的疗效和安全性研究[J].中国全科医学,2017,20(10):1200-1203,4.基金项目
北京市医院管理局临床医学发展专项经费资助项目 (ZYLX201507) （ZYLX201507）
