中国人兽共患病学报2017,Vol.33Issue(2):148-155,8.DOI:10.3969/j.issn.1002-2694.2017.02.011
几种新现人体隐孢子虫种和基因型流行现状
Epidemiology status of some new emerging Cryptosporidium species and genotypes in humans
摘要
Abstract
Cryptosporidium spp.are protozoan parasites that infect the epithelial cells of the gstrointestinal tract of hosts.In humans,cryptosporidiosis is usually a self-limiting infection in immunocompetent individuals,but severe diarrhea and dissemination to extra-intestinal sites can occur in high-risk individuals,such as the very young,the elderly,immunedeficiency individuals,particularly in HIV-positive patients.So far,molecular epidemiological data have confirmed the presence of 30 species and over 40 genotypes with genus Cryptosporidium,with 21 species and genotypes being found in humans.The majority of human cryptosporidiosis cases are responsible for C.hominis and C.parvum.Human cases caused by C.meleagridis,C.ubiquitum,C.felis and C.canis have been increasing.Besides that,with data accumulation of molecular epidemiology of human cryptosporidiosis,some more Cryptosporidium species and genotypes were newly identified in humans.This paper mainly reviews epidemiology status of these new emerging Cryptosporidium species and genotypes in humans.关键词
隐孢子虫/隐孢子虫病/分子流行病学Key words
Cryptosporidium/cryptosporidiosis/molecular epidemiology/humans分类
医药卫生引用本文复制引用
杨子吟,曹建平,沈玉娟,刘爱芹..几种新现人体隐孢子虫种和基因型流行现状[J].中国人兽共患病学报,2017,33(2):148-155,8.基金项目
Supported partially by the Chinese Special Program for Scientific Research of Public Health (No.201502021 and the Heilongjiang Province Education Bureau (No.12531266) (No.201502021 and the Heilongjiang Province Education Bureau (No.12531266)
国家卫生和计划生育委员会2015公益性行业科研专项(No.201502021)和黑龙江省教育厅课题(No.12531266)联合资助 (No.201502021)