中成药2017，Vol.39Issue(3)：504-508,5.DOI:10.3969/j.issn.1001-1528.2017.03.012
响应面法优化超声-微波提取甘草渣总黄酮工艺
Optimization of ultrasound-microwave extraction for total flavonoids from Glycyrrhizae Radix et Rhizoma residue by response surface method
摘要
Abstract
AIM To optimize the ultrasound-microwave extraction for total flavonoids from Glycyrrhizae Radix et Rhizoma residue by response surface method.METHODS In addition to the index of extraction rate of total flavonoids for evaluation,the microwave power,extraction time,liquid-soild ratio and ethanol concentration were taken into consideration as influencing factors for the extraction optimization by response surface method on the basis of single factor test.RESULTS The optimal conditions,determined to be 125 W for microwave power,32 min for extraction time,28.4 ∶ 1 for liquid-solid ratio,79％ for ethanol concentration,and 300 W for extraction power,could bring forth a 2.59％ extraction rate of total flavonoids.CONCLUSION This stable and reliable method can be used for extracting total flavonoids from Glycyrrhizae Radix et Rhizoma residue.关键词
甘草渣/总黄酮/超声-微波提取/响应面法Key words
Glycyrrhizae Radix et Rhizoma residue/total flavonoids/ultrasound-microwave extraction/response surface method分类
医药卫生引用本文复制引用
袁茹楠,胡浩斌,韩舜禹,王宗博..响应面法优化超声-微波提取甘草渣总黄酮工艺[J].中成药,2017,39(3):504-508,5.基金项目
甘肃省科技支撑项目(1604NKCM082) （1604NKCM082）
庆阳市科技合作项目(kh2014-03) （kh2014-03）
