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车前子酚类成分的研究

许兵兵 张丽 曾金祥 毕莹 王娟 任刚 王洪玲 李敏 邹红

中成药2017,Vol.39Issue(3):544-547,4.
中成药2017,Vol.39Issue(3):544-547,4.DOI:10.3969/j.issn.1001-1528.2017.03.021

车前子酚类成分的研究

Phenols from Plantaginis Semen

许兵兵 1张丽 2曾金祥 1毕莹 3王娟 1任刚 1王洪玲 1李敏 1邹红2

作者信息

  • 1. 江西中医药大学中药资源与民族药研究中心,江西南昌330004
  • 2. 江西中医药大学计划财务处,江西南昌330004
  • 3. 南昌市第三医院,江西南昌330009
  • 折叠

摘要

Abstract

AIM To study the phenols from Plantaginis Semen.METHODS The 65% and 95% ethanol extracts of Plantaginis Semen were isolated and purified by macroporous resin,silica,ODS,Sephadex and preparative column,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Nine compounds were isolated and identified as (+)-(7R,7'R,8S,8'S)-neo-olivil (1),erythro-guaiacylglycerol-β-ferulic acid ether (2),eriodictyol (3),luteolin (4),chrysoeriol (5),hydroxytyrosol (6),4-(3,4-dihydroxyphenyl)-(E)-3-buten-2-one (7),ferulic acid (8),5,7-dihydroxychromone (9).CONCLUSION Compounds 2-3,6-7 and 9 are isolated from genus Plantago for the first time,compound 5 is first obtained from this plant.

关键词

车前子/酚类/分离鉴定

Key words

Plantaginis Semen/phenols/isolation and identification

分类

医药卫生

引用本文复制引用

许兵兵,张丽,曾金祥,毕莹,王娟,任刚,王洪玲,李敏,邹红..车前子酚类成分的研究[J].中成药,2017,39(3):544-547,4.

基金项目

国家自然科学基金(81260630) (81260630)

江西省卫生厅项目(2015B047) (2015B047)

中成药

OA北大核心CSCDCSTPCD

1001-1528

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